What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized? a. The origins of replication occur only at the 5′ end. b. Helicases and single-strand binding proteins work at the 5′ end. c. DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel. d. DNA ligase works only in the 3′→5′ direction.

Video transcript

Hello everyone here. We have a question telling us. DNA preliminaries can join new nucleotides only to the three prime end of a preexisting strands and the strands are anti parallel. This will provide the basis for a the leading and lagging strands of D. N. A. B. Formation of Okazaki fragments C. Origin of replication D. Both leading and lagging strand and Okazaki fragments. E. DNA lies and single stranded binding proteins. So we have our D. N. A polymerase adding to the three prime end of our pre existing strand and our two strands are anti parallel, so they're being added to opposite ends. So we have one going towards the replication fork and it is called our leading strand and we have one going away from the replication fork and it is our lagging strand and are lagging strand is synthesized in short fragments that are called Okazaki fragments. So as we can see, this provides the basis for both leading and lagging strand and Okazaki fragments. Because the lagging strand is composed of these Okazaki fragments. So our answer here is the both leading and lagging strand and Okazaki fragments. Thank you for watching. Bye.