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Innate Immunity definitions Flashcards

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Innate Immunity definitions
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  • Innate Immune System


    The body's first line of defense against pathogens, providing a rapid, non-specific response through barriers, phagocytes, and signaling molecules to prevent infection and initiate inflammation.

  • Pathogens


    Microorganisms or agents that cause disease in their host, including bacteria, viruses, fungi, and parasites.

  • Skin


    The body's outermost layer, acting as a physical barrier to protect internal tissues from pathogens, while also playing a role in the innate immune response.

  • Mucus


    A viscous secretion that traps pathogens at body openings, contains antimicrobial enzymes, and aids in their expulsion, providing a non-specific defense mechanism in the innate immune system.

  • Lysozymes


    Enzymes that degrade bacterial cell walls, found in mucus and other body fluids, providing a nonspecific defense against pathogens.

  • Leukocytes


    White blood cells that play a crucial role in the body's immune response by identifying and eliminating pathogens through various mechanisms, including phagocytosis and cytokine release.

  • Pathogen Associated Molecular Patterns


    Molecules on pathogens recognized by the innate immune system, triggering a non-specific immune response.

  • Lipopolysaccharides


    Molecules on bacterial cell surfaces that trigger the innate immune response by acting as pathogen-associated molecular patterns (PAMPs) recognized by pattern recognition receptors (PRRs).

  • Pattern Recognition Receptors


    Membrane receptors on immune cells that detect pathogen-associated molecular patterns (PAMPs) to trigger an innate immune response.

  • Toll Like Receptors


    Membrane receptors on immune cells that recognize pathogen-associated molecular patterns, triggering a signaling cascade to recruit other immune cells and initiate an immune response.

  • Neutrophils


    Phagocytic white blood cells that circulate in the blood, attracted to infection sites by cytokines, engulf and digest pathogens, acting as mobile warriors in the innate immune system.

  • Macrophages


    Immune cells that reside in tissues, engulf pathogens, and release signals to recruit other immune cells, playing a key role in both innate and adaptive immunity.