Describe the mechanisms of extrinsic regulation of GFR, and their physiological role.

Video transcript

Hello, everyone and welcome to today's video. So today, we need to determine which of the following statements concerning extrinsic regulation of gar is inaccurate. Now, we're given four statements and we're going to be going over each of them and explaining why they're accurate or inaccurate so that we can solve this question. We're going to begin by answer choices. See and z now the reason why we're looking at both of them together is because they complement each other. Now for answer choice C we have that low blood pressure causes the glo the granular cells of the glomerular complex to release rein. And then for answer choice D we have Rain activist angiotensin two which promotes vasal constriction and enhance rice's blood pressure. Now, if we have a low blood pressure, then vasal construction or just the construction of these blood vessels is going to help us raise blood pressure. It is going to increase the pressure of the blood within the blood vessels because we're constricting them. So the blood flow is increased. Now, this action is definitely done by running according to previous videos. Therefore, these two statements are going to be correct and we can cancel both of them out because remember that we're looking for the incorrect statement or the inaccurate statement moving on, we have the, we have that viso construction of the OLS decreases GFR thereby restoring blood volume and pressure to normal. This is also a true statement. So we're going to move on. Finally, we have a which is that high blood pressure stimulates the sympathetic nerve fibers to produce, which causes vasoconstriction. Well, remember from taking a look at answer choices C and D that if we have high blood pressure and we undergo vasoconstriction, this is going to increase this pressure even more, which is not what the body wants. If we have high blood pressure, we're going to need vasodilation to take place so it can go back to normal. However, this is not what's happening here now, no is going to cause vasoconstriction, which is what we have here. However, this is not going to happen when we have high blood pressure, it's going to happen when we have low blood pressure. So the statement is partially incorrect and we can highlight it as a final answer to our question. A high blood pressure stimulates the sympathetic nerve fibers to produce no, which causes vasal construction is the final answer to our question. I really hope this video helped you and I hope to see you on the next one.