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Ch. 21 The Immune System: Innate and Adaptive Body Defenses
Chapter 20, Problem 23

Differentiate between humoral and cellular adaptive immunity.

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1
Understand that adaptive immunity is a specific defense mechanism that involves the recognition of specific antigens.
Identify that humoral immunity is mediated by B cells and involves the production of antibodies that circulate in body fluids.
Recognize that cellular immunity is mediated by T cells and involves the direct attack on infected or abnormal cells.
Note that humoral immunity is effective against extracellular pathogens, such as bacteria and viruses in the bloodstream.
Acknowledge that cellular immunity is effective against intracellular pathogens, such as viruses and some bacteria that reside within host cells.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Humoral Immunity

Humoral immunity is a component of the adaptive immune system that involves the production of antibodies by B cells. These antibodies circulate in the bloodstream and bind to specific antigens, neutralizing pathogens or marking them for destruction by other immune cells. This type of immunity is particularly effective against extracellular pathogens, such as bacteria and viruses in their free form.
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Cellular Immunity

Cellular immunity, also known as cell-mediated immunity, involves T cells that directly attack infected or cancerous cells. Unlike humoral immunity, which relies on antibodies, cellular immunity is crucial for eliminating intracellular pathogens, such as viruses that have invaded host cells. T cells can also help regulate the immune response and enhance the activity of other immune cells.
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Adaptive Immunity

Adaptive immunity is a specialized immune response that develops over time and provides long-lasting protection against specific pathogens. It is characterized by its ability to remember previous encounters with pathogens, allowing for a more rapid and effective response upon re-exposure. Both humoral and cellular immunity are integral parts of adaptive immunity, working together to provide comprehensive defense against infections.
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