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Ch. 21 The Respiratory System
Chapter 21, Problem 21.3a

Predict what would happen to the tidal volume and inspiratory reserve volume if the phrenic nerves were severed. Which muscles would contract to try to compensate for this?

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Understand that the phrenic nerves are responsible for innervating the diaphragm, which is the primary muscle involved in breathing.
Recognize that if the phrenic nerves are severed, the diaphragm would be paralyzed, leading to a significant reduction in tidal volume, as the diaphragm cannot contract to facilitate normal inhalation.
Consider that the inspiratory reserve volume would also decrease because the diaphragm's inability to contract would limit the capacity to take a deep breath beyond the normal tidal volume.
Identify that accessory muscles of respiration, such as the intercostal muscles, sternocleidomastoid, and scalene muscles, would attempt to compensate by contracting to elevate the rib cage and increase thoracic volume.
Acknowledge that while these accessory muscles can aid in breathing, they are not as effective as the diaphragm, and breathing would be more labored and less efficient.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Tidal Volume

Tidal volume refers to the amount of air inhaled or exhaled during normal breathing. It is a critical measure of lung function and respiratory health. If the phrenic nerves, which innervate the diaphragm, are severed, the tidal volume would likely decrease due to the diaphragm's inability to contract effectively, leading to shallower breaths.
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Inspiratory Reserve Volume

Inspiratory reserve volume (IRV) is the additional amount of air that can be inhaled after a normal inhalation. Severing the phrenic nerves would impair the diaphragm's function, potentially reducing the IRV as the body struggles to take deeper breaths. This could lead to a reliance on accessory muscles for deeper inhalation.
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Accessory Muscles of Breathing

Accessory muscles of breathing, such as the sternocleidomastoid and scalene muscles, assist in inhalation, especially when the diaphragm is compromised. If the phrenic nerves are severed, these muscles would contract more actively to compensate for the reduced tidal volume and inspiratory reserve volume, allowing for some degree of ventilation despite the loss of diaphragm function.
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Related Practice
Textbook Question

If you swallow a large bite of food without properly chewing it first, you will feel discomfort during ventilation. Explain this, considering the arrangement of the trachea and the esophagus.

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Textbook Question

What happens to the metabolic rate of skeletal muscle tissue during exercise? What waste products are produced from metabolic reactions? How and why does this affect your rate of ventilation during exercise?

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Textbook Question

You and a friend are having a contest to see who can hold his or her breath the longest. Your friend hyperventilates before holding his breath, and subsequently wins the contest. Why did hyperventilation give him an advantage?

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Textbook Question

Which of the following statements about pulmonary ventilation is false?


a. Normal expiration requires the use of the expiratory muscles to decrease lung volume.

b. The inspiratory muscles increase lung volume, which decreases intrapulmonary pressure.

c. For inspiration to occur, intrapulmonary pressure must decrease below atmospheric pressure.

d. The intrapleural pressure is less than the intrapulmonary pressure; this prevents the lungs from collapsing during expiration.

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Textbook Question

Match each term with the correct definition     


____Airway resistance     

____Surface tension     

____Surfactant     

____Pulmonary compliance     

____V/Q ratio


a. A detergent-like chemical secreted by bronchial smooth muscle that reduces surface tension

b. The matching of ventilation to perfusion

c. Largely determined by the diameter of the airways

d. Caused by the formation of hydrogen bonds between water molecules

e. Determined by the surface tension of the alveoli, the elastic tissue of the lungs, and the condition of the chest wall

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