When we previously introduced respiration, we said that carbon dioxide and oxygen are always moving down their pressure gradients between the air and the blood and between the blood and the tissues. Well, now we want to look at this in a little bit more detail. We're going to put some values on those gradients, and we're going to look at the nitty gritty. Before we really get into it, though, we need to note that the composition of atmospheric air is actually different than the air in the alveoli. So previously, we've been talking about atmospheric air and you can see those numbers here. You'll note they may be a little different than what we've seen before. It's okay. They're close enough. The one major difference here, we pulled argon out because we don't really care about that physiologically and we put water vapor in instead because that is going to be a little important. Alright. But these numbers, that's not actually part of the gradient that we're talking about. The gradient is between the air and the alveoli in the blood, and the composition of the air in the alveoli well, you can see here you can look at those numbers. They're pretty much different across the board. Now importantly, one number that is not different is going to be that total pressure. In both the alveoli and the atmospheric air, the total pressure is at 760 millimeters of mercury because remember that intrapulmonary pressure always equalizes to atmospheric pressure during ventilation. Alright. But we can go through this, and the first thing that we'll see here is that that water vapor there's way more water vapor in the lungs than in the atmospheric air. And that means that sort of more of that total pressure in the lungs is going to be taken up by that water vapor. And that's just because, right, it's wet inside your body. So in your lungs, that air is just very humid. Alright. But we can go now to carbon dioxide and oxygen. Those are the molecules we really care about, and you can see here look at that percent composition for carbon dioxide. There's over 100 times the percentage of carbon dioxide in your lungs than in the air around you and that converts to over 100 times the partial pressure in that alveoli. Now that's because during ventilation, right, your tidal volume is only 500 milliliters, but the residual capacity, the amount of air that doesn't move out of your lungs with every breath, is something like closer to 2 liters. So you're only replenishing a bit of that air with each breath, and that carbon dioxide is just always moving from the blood into the alveoli, so that partial pressure is much higher than in the atmosphere here. Well, the opposite is going to be true for the oxygen. You can see here there's much less oxygen in the alveoli compared to the atmospheric air, and that converts to significantly lower partial pressure due to oxygen in the alveoli than in the atmospheric air. You'll note the difference is relatively not nearly as great compared to the difference for carbon dioxide, but it is significant. Alright. Finally, there's nitrogen. Nitrogen is not that interesting physiologically. You'll note that it's a little bit different there, but we don't worry about that. The big thing here though is that I'm just going to gray out this atmospheric air, those columns there, because we don't care about them. What's important is those partial pressures in the alveoli and specifically the partial pressures for oxygen and carbon dioxide. These are numbers you might want to remember. Partial pressure for oxygen is going to be 104. Partial pressure for carbon dioxide is going to be 40 millimeters of mercury in the alveoli. Alright. Let's take a look at this now. Alright. We are going to be talking about 2 gradients that determine the movement of the gases in the body, and that's going to
Table of contents
- 1. Introduction to Anatomy & Physiology5h 40m
- What is Anatomy & Physiology?20m
- Levels of Organization13m
- Variation in Anatomy & Physiology12m
- Introduction to Organ Systems27m
- Homeostasis9m
- Feedback Loops11m
- Feedback Loops: Negative Feedback19m
- Feedback Loops: Positive Feedback11m
- Anatomical Position7m
- Introduction to Directional Terms3m
- Directional Terms: Up and Down9m
- Directional Terms: Front and Back6m
- Directional Terms: Body Sides12m
- Directional Terms: Limbs6m
- Directional Terms: Depth Within the Body4m
- Introduction to Anatomical Terms for Body Regions3m
- Anatomical Terms for the Head and Neck8m
- Anatomical Terms for the Front of the Trunk8m
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- Review- Using Anatomical Terms and Directions12m
- Abdominopelvic Quadrants and Regions19m
- Anatomical Planes & Sections17m
- Organization of the Body: Body Cavities13m
- Organization of the Body: Serous Membranes14m
- Organization of the Body: Serous Membrane Locations8m
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- Organization of the Body: Abdominopelvic Cavity12m
- 2. Cell Chemistry & Cell Components12h 37m
- Atoms- Smallest Unit of Matter57m
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- Introduction to Chemical Bonding19m
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- 4. Tissues & Histology10h 3m
- Introduction to Tissues & Histology16m
- Introduction to Epithelial Tissue24m
- Characteristics of Epithelial Tissue37m
- Structural Naming of Epithelial Tissue19m
- Simple Epithelial Tissues1h 2m
- Stratified Epithelial Tissues55m
- Identifying Types of Epithelial Tissue32m
- Glandular Epithelial Tissue26m
- Introduction to Connective Tissue36m
- Classes of Connective Tissue8m
- Introduction to Connective Tissue Proper40m
- Connective Tissue Proper: Loose Connective Tissue56m
- Connective Tissue Proper: Dense Connective Tissue49m
- Specialized Connective Tissue: Cartilage44m
- Specialized Connective Tissue: Bone12m
- Specialized Connective Tissue: Blood9m
- Introduction to Muscle Tissue7m
- Types of Muscle Tissue45m
- Introduction to Nervous Tissue8m
- Nervous Tissue: The Neuron8m
- 5. Integumentary System2h 20m
- 6. Bones & Skeletal Tissue2h 16m
- An Introduction to Bone and Skeletal Tissue18m
- Gross Anatomy of Bone: Compact and Spongy Bone7m
- Gross Anatomy of Bone: Periosteum and Endosteum11m
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- Gross Anatomy of Bone: Short, Flat, and Irregular Bones5m
- Gross Anatomy of Bones - Structure of a Long Bone23m
- Microscopic Anatomy of Bones - Bone Matrix9m
- Microscopic Anatomy of Bones - Bone Cells25m
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- Microscopic Anatomy of Bones - Trabeculae9m
- 7. The Skeletal System2h 35m
- 8. Joints2h 17m
- 9. Muscle Tissue2h 33m
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- 11. Nervous Tissue and Nervous System1h 35m
- 12. The Central Nervous System1h 6m
- 13. The Peripheral Nervous System1h 26m
- Introduction to the Peripheral Nervous System5m
- Organization of Sensory Pathways16m
- Introduction to Sensory Receptors5m
- Sensory Receptor Classification by Modality6m
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- Proprioceptors7m
- Adaptation of Sensory Receptors8m
- Introduction to Reflex Arcs13m
- Reflex Arcs15m
- 14. The Autonomic Nervous System1h 38m
- 15. The Special Senses2h 41m
- 16. The Endocrine System2h 48m
- 17. The Blood1h 22m
- 18. The Heart1h 42m
- 19. The Blood Vessels3h 35m
- 20. The Lymphatic System3h 16m
- 21. The Immune System14h 37m
- Introduction to the Immune System10m
- Introduction to Innate Immunity17m
- Introduction to First-Line Defenses5m
- Physical Barriers in First-Line Defenses: Skin13m
- Physical Barriers in First-Line Defenses: Mucous Membrane9m
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- First-Line Defenses: Normal Microbiota7m
- Introduction to Cells of the Immune System15m
- Cells of the Immune System: Granulocytes28m
- Cells of the Immune System: Agranulocytes26m
- Introduction to Cell Communication5m
- Cell Communication: Surface Receptors & Adhesion Molecules16m
- Cell Communication: Cytokines27m
- Pattern Recognition Receptors (PRRs)48m
- Introduction to the Complement System24m
- Activation Pathways of the Complement System23m
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- Review of the Complement System13m
- Phagocytosis17m
- Introduction to Inflammation18m
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- Fever8m
- Interferon Response25m
- Review Map of Innate Immunity
- Introduction to Adaptive Immunity32m
- Antigens12m
- Introduction to T Lymphocytes38m
- Major Histocompatibility Complex Molecules20m
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- Functions of T Lymphocytes25m
- Review of Cytotoxic vs Helper T Cells13m
- Introduction to B Lymphocytes27m
- Antibodies14m
- Classes of Antibodies35m
- Outcomes of Antibody Binding to Antigen15m
- T Dependent & T Independent Antigens21m
- Clonal Selection20m
- Antibody Class Switching17m
- Affinity Maturation14m
- Primary and Secondary Response of Adaptive Immunity21m
- Immune Tolerance28m
- Regulatory T Cells10m
- Natural Killer Cells16m
- Review of Adaptive Immunity25m
- 22. The Respiratory System3h 20m
- 23. The Digestive System2h 5m
- 24. Metabolism and Nutrition4h 0m
- Essential Amino Acids5m
- Lipid Vitamins19m
- Cellular Respiration: Redox Reactions15m
- Introduction to Cellular Respiration22m
- Cellular Respiration: Types of Phosphorylation14m
- Cellular Respiration: Glycolysis19m
- Cellular Respiration: Pyruvate Oxidation8m
- Cellular Respiration: Krebs Cycle16m
- Cellular Respiration: Electron Transport Chain14m
- Cellular Respiration: Chemiosmosis7m
- Review of Aerobic Cellular Respiration18m
- Fermentation & Anaerobic Respiration23m
- Gluconeogenesis16m
- Fatty Acid Oxidation20m
- Amino Acid Oxidation17m
- 25. The Urinary System2h 39m
- 26. Fluid and Electrolyte Balance, Acid Base Balance Coming soon
- 27. The Reproductive System2h 5m
- 28. Human Development1h 21m
- 29. Heredity Coming soon
22. The Respiratory System
Respiration
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