17. The Blood
Platelets: Hemostasis
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Platelets: Hemostasis practice set
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In this video, we're going to talk about 2 different memory tools to help us remember the important coagulation components. And so the first memory tool is over here on the left hand side, and the second memory tool is over here on the right hand side. Now with the first memory tool, notice that we've got this old fellow right here, and he is actually an ex track and field star that is actually in the hall of fame. And believe it or not he only retired 3 years ago with a total of 12 gold medals. Now, notice that the bolded and underlined letters that you see here can help us remember that the extrinsic pathway of blood coagulation is triggered by tissue factor, And tissue factor is also known as factor number 3. And then the end hall of fame, again the bolded and underlined letters can help us remember that the intrinsic pathway of blood coagulation is triggered by Hageman Factor, and Hageman Factor is also known as factor number 12. And so hopefully, just by remembering ex track and field star in the hall of fame, that will help you remember some of these important details. Now over here on the right hand side, we've got another memory tool that is more specific to remembering the details about the important coagulation factors and the order that they are involved in in the pathway. And so this memory tool is just platelets packed tightly for fibrin. And so notice in the image up above here, what we have are some really tightly packed platelets that don't seem to be too happy about that. And over here on the right, what we have is the platelet plug that is reinforced with fibrin, and so it's forming this blood clot. And we know that fibrin is the end result and the main goal of blood coagulation, so that that fibrin can serve as the glue that reinforces and stabilizes the platelet plug. And so just by remembering platelets packed tightly for fibrin, that can really help with putting these important coagulation, components in the correct order. And so the P in platelets is for the P in prothrombin activator, and the P in PAC is for the P in prothrombin. Now because they both start with p, of course, it's the activator, the prothrombin activator, that must come first because the prothrombin activator must activate prothrombin. And so, that can hopefully be helpful there. Platelets pack, And then tightly is going to be for thrombin. The t in tightly is for the t in thrombin. The f, in 4 is for the F in fibrinogen, and the F in fibrin is for the F in fibrin. Now, we know that the end result of blood coagulation is to produce the fibrin, and so fibrin is going to be last, but fibrinogen is going to come just before. And so, again, just by remembering platelets packed tightly for fibrin, that can be very helpful and effective, in remembering these important coagulation factors in the correct order. And so this here concludes our brief lesson on how to remember the important coagulation components, and I'll see you all in our next video.
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