In this video, we're going to begin our introduction to immunity. And so when our bodies are attacked by foreign microbes, we actually have various defense mechanisms to help protect us from those attacking microbes. And so we collectively refer to these defense mechanisms as our immunity. And so immunity can be defined as our ability to eliminate disease-causing microbes from our bodies and to help protect our bodies against environmental agents such as pollen, for example. Now, susceptibility on the other hand refers to the lack of immunity towards some kind of agent. Now our immune systems are really broken up into 2 major groups. And so really there are 2 general types of immunity. The first is going to be innate immunity, and the second is going to be adaptive immunity. Now innate immunity is also sometimes referred to as nonspecific immunity. And so, innate implies that this is going to provide routine protection that is present at birth, and that's really what this innate term refers to. That the fact that we are born with these innate protective immune responses. Now, the reason that it is also referred to as nonspecific immunity is because this type of immunity protects us against a very broad range of many different types of pathogens. Now the second major group of our immune system is going to be adaptive immunity. And adaptive immunity is also sometimes referred to as specific immunity. And so the adaptive part of adaptive immunity implies that it includes components that are capable of adapting or changing over time. And that means that as we expose ourselves to new environments and different types of environmental agents, our adaptive immune responses are capable of changing and adapting and evolving to become better at protecting us over time. And, it is also referred to as specific immunity because this type of immunity will provide us with protection against very specific types of pathogens. Now as we move forward in our course, we're going to talk a lot more details about both innate or nonspecific immunity first, and then we'll talk a lot more details about adaptive or specific immunity much later. However, it is important to know that although generally, innate and adaptive immunity are taught separately, that some parts of innate immunity will complement some parts of adaptive immunity and vice versa. And so there is a little bit of cross-talk between innate immune responses and adaptive immune responses. And as we move forward in our course, that's important to keep in mind and it is also going to be something that we will try to make connections between the 2 as we move forward in our course. And so if we take a look at our image down below, notice that the left-hand side over here is focused specifically on innate immunity, which once again recall is also referred to as nonspecific immunity that provides routine protection that is present at birth against the broad range of many different types of pathogens. And innate immunity includes things such as physical barriers, such as our skin, and mucus membranes. It also includes chemical defenses such as antimicrobials, acids, bases, and things of that nature. And we'll get to talk a lot more about these chemical defenses as we move forward in our course. And it also includes a collection of several different innate immune cells, which once again, we'll get to talk a lot more details about them as we move forward in our course. Now over here, the right side of the image is focused specifically on adaptive immunity. And once again, adaptive immunity is also referred to as specific immunity and it includes components that adapt or change over time in response to changing environments and also exposure to different types of pathogens. And, adaptive or specific immunity provides protection against very specific types of pathogens. And adaptive immunity includes antibodies, which are these y-shaped proteins that are capable of binding to foreign molecules and generating some kind of immune response, And we'll get to talk a lot more about antibodies as we move forward in our course. And adaptive immunity also includes adaptive immune cells, such as for example, b cells and t cells. And again, we'll get to talk a lot more about the adaptive immune cells as we move forward in our course as well. But for now, this here concludes our brief introduction to immunity and how our immune systems are broken up into 2 major categories, innate immunity and adaptive immunity. And again, there is sometimes going to be some parts of each type of immunity that are going to complement each other and they work together in some cases. And so, we will get to learn a lot more as we move forward so I'll see you all in our next video.
Table of contents
- 1. Introduction to Anatomy & Physiology5h 40m
- What is Anatomy & Physiology?20m
- Levels of Organization13m
- Variation in Anatomy & Physiology12m
- Introduction to Organ Systems27m
- Homeostasis9m
- Feedback Loops11m
- Feedback Loops: Negative Feedback19m
- Feedback Loops: Positive Feedback11m
- Anatomical Position7m
- Introduction to Directional Terms3m
- Directional Terms: Up and Down9m
- Directional Terms: Front and Back6m
- Directional Terms: Body Sides12m
- Directional Terms: Limbs6m
- Directional Terms: Depth Within the Body4m
- Introduction to Anatomical Terms for Body Regions3m
- Anatomical Terms for the Head and Neck8m
- Anatomical Terms for the Front of the Trunk8m
- Anatomical Terms for the Back9m
- Anatomical Terms for the Arm and Hand9m
- Anatomical Terms for the Leg and Foot15m
- Review- Using Anatomical Terms and Directions12m
- Abdominopelvic Quadrants and Regions19m
- Anatomical Planes & Sections17m
- Organization of the Body: Body Cavities13m
- Organization of the Body: Serous Membranes14m
- Organization of the Body: Serous Membrane Locations8m
- Organization of the Body: Thoracic Cavity8m
- Organization of the Body: Abdominopelvic Cavity12m
- 2. Cell Chemistry & Cell Components12h 37m
- Atoms- Smallest Unit of Matter57m
- Isotopes39m
- Introduction to Chemical Bonding19m
- Covalent Bonds40m
- Noncovalent Bonds5m
- Ionic Bonding37m
- Hydrogen Bonding19m
- Introduction to Water7m
- Properties of Water- Cohesion and Adhesion7m
- Properties of Water- Density8m
- Properties of Water- Thermal14m
- Properties of Water- The Universal Solvent17m
- Acids and Bases12m
- pH Scale21m
- Carbon8m
- Functional Groups9m
- Introduction to Biomolecules2m
- Monomers & Polymers11m
- Carbohydrates23m
- Proteins25m
- Nucleic Acids34m
- Lipids28m
- Microscopes10m
- Prokaryotic & Eukaryotic Cells26m
- Introduction to Eukaryotic Organelles16m
- Endomembrane System: Protein Secretion34m
- Endomembrane System: Digestive Organelles15m
- Mitochondria & Chloroplasts21m
- Endosymbiotic Theory10m
- Introduction to the Cytoskeleton10m
- Cell Junctions8m
- Biological Membranes10m
- Types of Membrane Proteins7m
- Concentration Gradients and Diffusion9m
- Introduction to Membrane Transport14m
- Passive vs. Active Transport13m
- Osmosis33m
- Simple and Facilitated Diffusion17m
- Active Transport30m
- Endocytosis and Exocytosis15m
- 3. Energy & Cell Processes10h 7m
- Introduction to Energy15m
- Laws of Thermodynamics15m
- Chemical Reactions9m
- ATP20m
- Enzymes14m
- Enzyme Activation Energy9m
- Enzyme Binding Factors9m
- Enzyme Inhibition10m
- Introduction to Metabolism8m
- Redox Reactions15m
- Introduction to Cellular Respiration22m
- Types of Phosphorylation11m
- Glycolysis19m
- Pyruvate Oxidation8m
- Krebs Cycle16m
- Electron Transport Chain14m
- Chemiosmosis7m
- Review of Aerobic Cellular Respiration19m
- Fermentation & Anaerobic Respiration23m
- Introduction to Cell Division22m
- Organization of DNA in the Cell17m
- Introduction to the Cell Cycle7m
- Interphase18m
- Phases of Mitosis48m
- Cytokinesis16m
- Cell Cycle Regulation18m
- Review of the Cell Cycle7m
- Cancer13m
- Introduction to DNA Replication22m
- DNA Repair7m
- Central Dogma7m
- Introduction to Transcription20m
- Steps of Transcription19m
- Genetic Code25m
- Introduction to Translation30m
- Steps of Translation23m
- Post-Translational Modification6m
- 4. Tissues & Histology10h 3m
- Introduction to Tissues & Histology16m
- Introduction to Epithelial Tissue24m
- Characteristics of Epithelial Tissue37m
- Structural Naming of Epithelial Tissue19m
- Simple Epithelial Tissues1h 2m
- Stratified Epithelial Tissues55m
- Identifying Types of Epithelial Tissue32m
- Glandular Epithelial Tissue26m
- Introduction to Connective Tissue36m
- Classes of Connective Tissue8m
- Introduction to Connective Tissue Proper40m
- Connective Tissue Proper: Loose Connective Tissue56m
- Connective Tissue Proper: Dense Connective Tissue49m
- Specialized Connective Tissue: Cartilage44m
- Specialized Connective Tissue: Bone12m
- Specialized Connective Tissue: Blood9m
- Introduction to Muscle Tissue7m
- Types of Muscle Tissue45m
- Introduction to Nervous Tissue8m
- Nervous Tissue: The Neuron8m
- 5. Integumentary System2h 20m
- 6. Bones & Skeletal Tissue2h 16m
- An Introduction to Bone and Skeletal Tissue18m
- Gross Anatomy of Bone: Compact and Spongy Bone7m
- Gross Anatomy of Bone: Periosteum and Endosteum11m
- Gross Anatomy of Bone: Bone Marrow8m
- Gross Anatomy of Bone: Short, Flat, and Irregular Bones5m
- Gross Anatomy of Bones - Structure of a Long Bone23m
- Microscopic Anatomy of Bones - Bone Matrix9m
- Microscopic Anatomy of Bones - Bone Cells25m
- Microscopic Anatomy of Bones - The Osteon17m
- Microscopic Anatomy of Bones - Trabeculae9m
- 7. The Skeletal System2h 35m
- 8. Joints2h 17m
- 9. Muscle Tissue2h 33m
- 10. Muscles1h 11m
- 11. Nervous Tissue and Nervous System1h 35m
- 12. The Central Nervous System1h 6m
- 13. The Peripheral Nervous System1h 26m
- Introduction to the Peripheral Nervous System5m
- Organization of Sensory Pathways16m
- Introduction to Sensory Receptors5m
- Sensory Receptor Classification by Modality6m
- Sensory Receptor Classification by Location8m
- Proprioceptors7m
- Adaptation of Sensory Receptors8m
- Introduction to Reflex Arcs13m
- Reflex Arcs15m
- 14. The Autonomic Nervous System1h 38m
- 15. The Special Senses2h 41m
- 16. The Endocrine System2h 48m
- 17. The Blood1h 22m
- 18. The Heart1h 42m
- 19. The Blood Vessels3h 35m
- 20. The Lymphatic System3h 16m
- 21. The Immune System14h 37m
- Introduction to the Immune System10m
- Introduction to Innate Immunity17m
- Introduction to First-Line Defenses5m
- Physical Barriers in First-Line Defenses: Skin13m
- Physical Barriers in First-Line Defenses: Mucous Membrane9m
- First-Line Defenses: Chemical Barriers24m
- First-Line Defenses: Normal Microbiota7m
- Introduction to Cells of the Immune System15m
- Cells of the Immune System: Granulocytes28m
- Cells of the Immune System: Agranulocytes26m
- Introduction to Cell Communication5m
- Cell Communication: Surface Receptors & Adhesion Molecules16m
- Cell Communication: Cytokines27m
- Pattern Recognition Receptors (PRRs)48m
- Introduction to the Complement System24m
- Activation Pathways of the Complement System23m
- Effects of the Complement System23m
- Review of the Complement System13m
- Phagocytosis17m
- Introduction to Inflammation18m
- Steps of the Inflammatory Response28m
- Fever8m
- Interferon Response25m
- Review Map of Innate Immunity
- Introduction to Adaptive Immunity32m
- Antigens12m
- Introduction to T Lymphocytes38m
- Major Histocompatibility Complex Molecules20m
- Activation of T Lymphocytes21m
- Functions of T Lymphocytes25m
- Review of Cytotoxic vs Helper T Cells13m
- Introduction to B Lymphocytes27m
- Antibodies14m
- Classes of Antibodies35m
- Outcomes of Antibody Binding to Antigen15m
- T Dependent & T Independent Antigens21m
- Clonal Selection20m
- Antibody Class Switching17m
- Affinity Maturation14m
- Primary and Secondary Response of Adaptive Immunity21m
- Immune Tolerance28m
- Regulatory T Cells10m
- Natural Killer Cells16m
- Review of Adaptive Immunity25m
- 22. The Respiratory System3h 20m
- 23. The Digestive System2h 5m
- 24. Metabolism and Nutrition4h 0m
- Essential Amino Acids5m
- Lipid Vitamins19m
- Cellular Respiration: Redox Reactions15m
- Introduction to Cellular Respiration22m
- Cellular Respiration: Types of Phosphorylation14m
- Cellular Respiration: Glycolysis19m
- Cellular Respiration: Pyruvate Oxidation8m
- Cellular Respiration: Krebs Cycle16m
- Cellular Respiration: Electron Transport Chain14m
- Cellular Respiration: Chemiosmosis7m
- Review of Aerobic Cellular Respiration18m
- Fermentation & Anaerobic Respiration23m
- Gluconeogenesis16m
- Fatty Acid Oxidation20m
- Amino Acid Oxidation17m
- 25. The Urinary System2h 39m
- 26. Fluid and Electrolyte Balance, Acid Base Balance Coming soon
- 27. The Reproductive System2h 5m
- 28. Human Development1h 21m
- 29. Heredity Coming soon
21. The Immune System
Introduction to the Immune System
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