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Concepts of Genetics, 12th edition

Published by Pearson (July 30, 2021) © 2019

  • William S Klug The College of New Jersey
  • Michael Cummings
  • Charlotte A. Spencer University of Alberta
  • Michael A Palladino Monmouth University
  • Darrell Killian Colorado College
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Concepts of Genetics emphasizes the fundamental ideas of genetics while exploring modern techniques and applications of genetic analysis. This best-selling text provides understandable explanations of complex, analytical topics and recognizes the importance of equipping you to become an effective problem solver.

The 12th Edition provides comprehensive coverage of emerging topics, including CRISPR-Cas and the study of posttranscriptional gene regulation in eukaryotes. The feature, Genetics, Ethics, and Society and Case Study, emphasizes ethical considerations that genetics brings into everyday life.

I: GENES, CHROMOSOMES, AND HEREDITY

  1. Introduction to Genetics
  2. Mitosis and Meiosis
  3. Mendelian Genetics
  4. Extensions of Mendelian Genetics
  5. Chromosome Mapping in Eukaryotes
  6. Genetic Analysis and Mapping in Bacteria and Bacteriophages
  7. Sex Determination and Sex Chromosomes
  8. Chromosome Mutations: Variation in Number and Arrangemen
  9. Extranuclear Inheritance

II: DNA: STRUCTURE, REPLICATION, AND ORGANIZATION

  1. DNA Structure and Analysis
  2. DNA Replication and Recombination
  3. DNA Organization in Chromosomes

III: GENE EXPRESSION AND ITS REGULATION

  1. The Genetic Code and Transcription
  2. Translation and Proteins
  3. Gene Mutation, DNA Repair, and Transposition
  4. Regulation of Gene Expression in Bacteria
  5. Transcriptional Regulation in Eukaryotes
  6. Post-transcriptional Regulation in Eukaryotes
  7. Epigenetics

IV: GENETIC TECHNOLOGY AND GENOMICS

  1. Recombinant DNA Technology
  2. Genomic Analysis
  3. Applications of Genetic Engineering and Biotechnology

V: GENETIC ANALYSIS OF ORGANISMS AND POPULATIONS

  1. Developmental Genetics
  2. Cancer Genetics
  3. Quantitative Genetics and Multifactorial Traits
  4. Population and Evolutionary Genetics

SPECIAL TOPICS IN MODERN GENETICS

  • ST1 CRISPR and Genomic Editing
  • ST2 DNA Forensics
  • ST3 Genomics and Precision Medicine
  • ST4 Genetically Modified Foods
  • ST5 Gene Therapy
  • ST6 Advances in Neurogenetics: The Study of Huntington Disease

APPENDICES

  1. Selected Readings
  2. Answers to Selected Problems

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