Genetic Analysis: An Integrated Approach, Global Edition, 2nd edition

Develop Problem Solving Skills

• Genetic Analysis worked examples provide unparalleled support for problem solving instruction. Each Genetic Analysis example guides students with a unique, consistent three-step approach that trains them to Evaluate, Deduce, and then Solve problems. Every Genetic Analysis example is presented in a clear, easy-to-follow, two-column format that helps students see the Solution Strategy in one column and its corresponding execution in the Solution Step.
• NEW! “Break It Down” component has been added to each Genetic Analysis worked example to help students get started with formulating an approach to solving a problem. “Break It Down” models the concept of breaking down problem solving by deciphering the essential information stated in the problem.
• End-of-Chapter Problems are divided into separate sections labeled Chapter Concepts and Application and Integration. The book offers a broad range of question types and level of difficulty. Answers to even-numbered problems appear in the Appendix.

Engage Students in the Process of Science and Genetic Discoveries

• NEW! Integrated coverage of genomics throughout. Genomic investigations are rapidly expanding and changing what we know about genetics. Coverage of important techniques and findings are integrated throughout the text, such as a new discussion of the impact of lateral gene transfer on bacterial genomes in Chapter 6; a new Experimental Insight of cancer genomics in Chapter 12; discussions of new genome methods and analyses in Chapter 18; and updated coverage of the human genome, including data on interaction with Neandertals and Denisovans in Chapter 22.
• NEW! Revised and expanded coverage of epigenetics in Chapters 11 and 15. Coverage in Chapter 15 has been substantially rewritten to expand the discussion of epigenetics, including new information on the histone code and chromatin states, and on epigenetic readers, writers, and erasers.
• NEW! Expanded coverage of archaea molecular biology Recent advancements in understanding the genetics and molecular biology of archaea are described where appropriate. These recent findings allow insightful comparisons to the genetics of bacteria and eukaryotes, particularly in relation to molecular genetic processes and to evolution. New archaea discussions and descriptions appear in Chapters 7, 8, 9, 11, 12, and 14.
• NEW! Enhanced coverage of molecular evolution The text’s focus on evolution in genetics now includes more coverage of molecular evolution integrated into appropriate chapters. Chapters 7, 8 and 9 have expanded discussions of the evolution of the processes of replication, transcription, and translation. Chapter 11 discusses the evolution of histone proteins in archaea and eukaryotes. Chapter 14 describes evolutionary comparisons of regulatory mechanisms in archaea and bacteria. Chapter 15 contains expanded coverage of the evolution of regulatory functions. Chapter 22 contains new discussions of evolution at the population, species, and molecular levels.
• Experimental Insight essays discuss influential experiments, summarise real experimental data derived from the experiments, and explain conclusions drawn from the analysis of results.
• Research Technique boxes explore important research methods and visually illustrate the results and interpretations of the techniques.
• Unique Chapter 10: The Integration of Genetic Approaches integrates transmission genetics, molecular analysis, molecular techniques, and evolution in an exploration of human sickle cell disease.