Concepts of Genetics, Global Edition, 12th edition

Published by Pearson (February 26, 2019) © 2019

  • William S Klug The College of New Jersey
  • Michael Cummings
  • Charlotte A. Spencer University of Alberta
  • Michael A Palladino Monmouth University
  • Darrell Killian Colorado College
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For all introductory genetics courses

Concepts of Genetics emphasises the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. This best-selling text continues to provide understandable explanations of complex, analytical topics and recognises the importance of teaching students how to become effective problem solvers.

The 12th Edition has been extensively updated to provide comprehensive coverage of important, emerging topics such as CRISPR-Cas and the study of posttranscriptional gene regulation in eukaryotes. An expanded emphasis on ethical considerations that genetics is bringing into everyday life is addressed in Genetics, Ethics, and Society and Case Study features.

  • Part One - Genes, Chromosomes, and Heredity
  • 1 Introduction to Genetics
  • 2 Mitosis and Meiosis
  • 3 Mendelian Genetics
  • 4 Extensions of Mendelian Genetics
  • 5 Sex Determination and Sex Chromosomes
  • 6 Chromosomal Mutations: Variation in Number and Arrangement
  • 7 Chromosome Mapping in Eukaryotes
  • 8 Genetic Analysis and Mapping in Bacteria and Bacteriophages
  • 9 Extranuclear Inheritance
  • Part Two - DNA: Structure, Replication, and Organization
  • 10 DNA Structure and Analysis
  • 11 DNA Replication and Recombination
  • 12 DNA Organization in Chromosomes
  • Part Three - Gene Expression and Its Regulation
  • 13 The Genetic Code and Transcription
  • 14 Translation and Proteins
  • 15 Gene Mutation, DNA Repair, and Transposition
  • 16 Regulation of Gene Expression in Bacteria
  • 17 Transcriptional Regulation in Eukaryotes
  • 18 Posttranscriptional Regulation in Eukaryotes
  • 19 Epigenetic Regulation of Gene Expression
  • Part Four - Genomics
  • 20 Recombinant DNA Technology
  • 21 Genomic Analysis
  • 22 Applications of Genetic Engineering and Biotechnology
  • Part Five - Genetics of Organisms and Populations
  • 23 Developmental Genetics
  • 24 Cancer Genetics
  • 25 Quantitative Genetics and Multifactorial Traits
  • 26 Population and Evolutionary Genetics
  • Special Topics in Modern Genetics
  • ST1 CRISPR and Genome Editing
  • ST2 DNA Forensics
  • ST3 Genomics and Precision Medicine
  • ST4 Genetically Modified Foods
  • ST5 Gene Therapy
  • ST6 Advances in Neurogenetics: The Study of Huntington Disease
  • Appendix A Selected Readings
  • Appendix B Answers to Selected Problems

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