Guided course 04:19Understanding how to convert terminal alkynes to alkynides.Johnny Betancourt1998views18rank8comments
Guided course 02:57Using double dehydrohalogenation to perform alkynide synthesis.Johnny Betancourt1842views19rank17comments
Guided course 02:29Predict the final product of the following reaction sequence.Johnny Betancourt1560views17rank6comments
Textbook QuestionWhat is the major product of the reaction of 1 mol of propyne with each of the following reagents? j. the product of part i followed by 1-chloropropane370views
Textbook QuestionWhat is the major product of the reaction of 1 mol of propyne with each of the following reagents? i. sodium amide369views
Textbook QuestionShow how you might synthesize the following compounds, using acetylene and any suitable alkyl halides as your starting materials. If the compound given cannot be synthesized by this method, explain why. a.hex-1-yne b. hex-2-yne c. hex-3-yne535views
Textbook Questionb. Give two sets of reactants (each set including an alkyl halide and a nucleophile) that could be used to synthesize the following alkyne: CH3CH2C≡CCH2CH2CH2CH3505views
Textbook Question(•) Show the products of the following acetylide alkylation reactions. [Make sure your product has the correct number of carbons.] (a)406views
Textbook Question(•) Show the products of the following acetylide alkylation reactions. [Make sure your product has the correct number of carbons.] (c)360views
Textbook Question(••) LOOKING AHEAD Ethinylestradiol is a synthetic hormone mimic used as a contraceptive for its ability to prevent ovulation. Suggest a mechanism for the synthesis using sodium acetylide and estrone, followed by quenching with acid.353views
Textbook QuestionSuggest reagents you might use to generate the product from the given reactant. (a)340views
Textbook QuestionSuggest reagents you might use to generate the product from the given reactant. (c)339views
Textbook QuestionA student provided the product of the following reactions, but made a mistake. Identify the mistake, correct the mistake, and suggest a way for the student to avoid that mistake in the future. (b)374views
Textbook QuestionA student provided the product of the following reactions, but made a mistake. Identify the mistake, correct the mistake, and suggest a way for the student to avoid that mistake in the future. (a)334views
Textbook Question(••) In Chapter 10, you learned how to make an alkyne by acetylide alkylation with a 1° haloalkane. Suggest a mechanism by which this reaction occurs.492views
Textbook QuestionWhat is the product of the reaction of an ester with excess acetylide ion followed by the addition of pyridinium chloride?428views
Textbook Questionb. Explain why ethyne should be alkylated before, rather than after, nucleophilic addition.422views
Textbook QuestionSuggest an acetylide ion and a carbonyl that might be used to make the following products. (a) oct-4-yn-3-ol428views
Textbook QuestionSuggest an acetylide ion and a carbonyl that might be used to make the following products. (b) 2,6-dimethylhept-3-yn-2-ol338views
Textbook QuestionSuggest an acetylide ion and a carbonyl that might be used to make the following products. (c) 5-phenylhex-2-yn-1-ol384views
Textbook Question(•) Show the products of the following acetylide alkylation reactions. [Make sure your product has the correct number of carbons.](d) <IMAGE>317views
Textbook Question(••) The introduction of elimination reactions provides a second way to synthesize alkynes in a two-step process starting with an alkene. Suggest a mechanism for both steps of this process.<IMAGE>327views
Textbook Question(•••) When the reaction scheme in Assessment 12.63 is done on a monosubstituted alkene, at least three equivalents of base are needed. Reacting the product of step 2 with D―Cl (D is an isotope of H) incorporates deuterium at the terminal carbon. Explain these two observations.<IMAGE>339views
Textbook QuestionCalculate for the following acid–base reactions. Which is the best base to use to deprotonate acetylene and make the acetylide anion?(a) HO⁻ + H―C ≡ C―H ⇌ ⁻C ≡ C―H + H₂O288views
Textbook QuestionCalculate for the following acid–base reactions. Which is the best base to use to deprotonate acetylene and make the acetylide anion?(b) H₂N⁻ + H―C ≡ C―H ⇌ ⁻C ≡ C―H + H₃N304views
Textbook Question(•) Show the products of the following acetylide alkylation reactions. [Make sure your product has the correct number of carbons.](b) <IMAGE>329views
Textbook QuestionCalculate for the following acid–base reactions. Which is the best base to use to deprotonate acetylene and make the acetylide anion?(c) <IMAGE>319views
Textbook QuestionSuggest reagents you might use to generate the product from the given reactant.(b) <IMAGE>279views
Textbook QuestionA chemist is planning to synthesize 3-octyne by adding 1-bromobutane to the product obtained from the reaction of 1-butyne with sodium amide. Unfortunately, however, he forgot to order 1-butyne. How else can he prepare 3-octyne?297views
Textbook Questiona. Draw the product of each of the following reactions:1. CH3CH2C≡CH→2. CH3CH2Br1. NaNH2312views
Textbook QuestionShow how you might synthesize the following compounds, using acetylene and any suitable alkyl halides as your starting materials. If the compound given cannot be synthesized by this method, explain why.d.4-methylhex-2-ynee. 5-methylhex-2-ynef. cyclodecyne267views
Textbook Questiona. Show how the following compounds can be prepared, using ethyne as one of the starting materials:3. 2-methyl-3-hexyn-2-ol216views
Textbook Question(••••) A chemist attempted to do the following acetylide alkylation reaction but was unsuccessful in several attempts, producing only the original starting materials in each case. Explain why the reaction didn't work. [We describe one way to solve this problem in Chapter 13.]347views
Textbook QuestionUsing the given starting material, any necessary inorganic reagents and catalysts, and any carbon-containing compounds with no more than three carbons, indicate how each of the following compounds can be prepared: c. CH3CH2C≡CH --> CH3CH2C≡CCH2CH3436views
Textbook Question(••) Suggest a method for synthesizing the following alkynes using an alkyne and an alkyl halide. [There are two correct answers for each product.] (a)347views
Textbook QuestionShow how you would accomplish the following synthetic transformations. Show all intermediates. (c) < of reaction>465views
04:19
