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Organic Chemistry 2 Midterm - Part 3 of 4
SAMPLE

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21. Aldehydes and Ketones: Nucleophilic Addition / DIBAL / Problem 2

Rationalize why the carbonyl oxygen of the ester attacks the aluminum of DIBAL-H instead of the alkoxy oxygen in the following reaction.

Reaction diagram showing DIBAL-H interacting with an ester's carbonyl oxygen.

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