Consider the following compound labeled with the O-18 isotope of oxygen. When this compound is hydrolyzed using either aqueous acid or base, the O-18 label ends up with the resulting alcohol.
Explain how you would experimentally confirm the presence of the O-18 label in the alcohol. Note that O-18 is not radioactive.

• A. It can be confirmed using UV spectroscopy.
• B. It can be confirmed using mass spectrometry.
• C. It can be confirmed using IR spectroscopy.

Answer: (B)