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Identify the missing products.
Identify the bonds broken and formed in the reaction shown below. Identify whether the reactions are favored or not based on qualitative analysis of the following factors: i) entropy ii) enthalpy iii) overall
In the benzoin condensation, what is the role of the cyanide ion? Why does the reaction fail if the hydroxide ion is used instead?
a) The cyanide ion generates an electrophile, allowing the reaction to occur. If a hydroxide ion is used, the electrophile is not generated, and the reaction will not continue.
b) The cyanide ion deprotonates methanol, allowing the reaction to occur. If a hydroxide ion is used, the methanol is not deprotonated, and the reaction will not continue.
c) The cyanide ion creates an umpolung to the carbonyl carbon, allowing the reaction to occur. If a hydroxide ion is used, the polarity of the carbonyl carbon will not be inverted, and the reaction will not continue.
d) The cyanide ion removes an α-hydrogen, allowing the reaction to occur. If a hydroxide ion is used, the α-hydrogen is not removed, and the reaction will not continue.
Draw the structure of the products formed when cyclopentanone reacts with sodium cyanide.
Provide the starting molecule and the reagent needed to synthesize the cyanohydrin below.
Propose a synthesis scheme for the formation of 1-methylcyclopent-1-ene from cyclopentanol.
Draw a suitable mechanism for the reaction shown below.
Can the hydration of aldehydes and ketones also be catalyzed by a base instead of an acid? Explain why.
Identify the given compound as one of the following: