Enamine Alkylation and Acylation
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Enamine Alkylation and Acylation
3 problems
1PRACTICE PROBLEM
Provide the mechanism for the hydrolysis of the iminium salt shown below to produce the ketone.
Hint: The process begins with water attacking, followed by the loss of a proton. Next, protonation occurs on the nitrogen, allowing the amine to leave and yield a protonated ketone.
(Ignore stereochemistry)
2PRACTICE PROBLEM
Show how the following compound can be synthesized via an enamine intermediate using cyclopentanone as the starting material.
3PRACTICE PROBLEM
What reactants and reagents are necessary to synthesize the following compound via an enamine intermediate?
