Classify the solvent below as polar protic, polar aprotic, or nonpolar.
Classify the solvents given below as protic or aprotic.
i. acetone
ii. propanoic acid
Explain the reason why stronger bases such as sodium hydride (NaH) lead to a faster E2 elimination compared to sodium methoxide (CH3ONa) by using the reaction's coordinate diagram.
What is the possible mechanism for the elimination reaction shown below?
Draw the products expected to form in the E2 reaction of the alkyl halide shown below.
Arrange the following compounds in increasing order of their E2 reactivity.
For the following reaction, predict which elimination products will be formed. Identify the major product (if any).
trans-1-chloro-3-ethylcyclohexane + NaOC2H5 →
Which of the following 2,3-dibromobicyclo[2.2.1]heptane would undergo an elimination reaction much faster? Explain these large rate differences.
Show how the (S,S) and (R,R) stereoisomers of 1-chloro-1,2-diphenylpentane undergo E2 elimination to give the same cis diastereomer of the product.
What is the product obtained from the following alkyl halide when it undergoes an E1 reaction?
What is the corresponding E1 mechanism for the given reaction?