when-an-haloketone-reacts-with-the-hydroxide-ion-a-carboxylic-acid-is-formed-thi

Question

When an α-haloketone reacts with the hydroxide ion, a carboxylic acid is formed. This is known as a Favorskii reaction. Propose a suitable mechanism for the Favorskii reaction below. Hint: The first step is deprotonation of the α-carbon that is not bonded to Br, the second step is forming a three-membered ring, and in the third step HO⁻ acts as a nucleophile.

Mechanism of Favorskii reaction showing α-haloketone conversion to carboxylic acid.

Accepted Answer

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Answer

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Answer

Detailed mechanism of Favorskii reaction with steps including nucleophilic attack and ring formation.

Answer

Alternative detailed mechanism of Favorskii reaction illustrating nucleophilic attack and product formation.