5. Chirality
Enantiomeric Excess
5. Chirality Enantiomeric Excess
10PRACTICE PROBLEM
Consider a theoretical reaction that is designed to produce one enantiomer to the exclusion of the other. If difference in activation energy between enantiomer A and enantiomer B is 3.5 kcal/mol and enantiomer B has the lower activation energy, at what temperature would you produce enantiomer B in 99% ee?
Consider a theoretical reaction that is designed to produce one enantiomer to the exclusion of the other. If difference in activation energy between enantiomer A and enantiomer B is 3.5 kcal/mol and enantiomer B has the lower activation energy, at what temperature would you produce enantiomer B in 99% ee?