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Substitution Comparison

How can 1-propanol be converted to become the ion shown below?

What nucleophiles would react with 1-iodoheptane to form the following comp

Provide a reaction scheme showing the conversion of butylbenzene to 2-pheny

Show how the product can be prepared from the given starting compound. Use 

Which of the two substrates will be more reactive when subjected to a nucle

Give the major product of the substitution reaction shown below:

The specific rotation of a pure (R)-2-bromobutane solution is -23.1°. When 

Identify the substitution products formed when the compounds below react wi

Draw the major product(s) of the reaction shown below.

Determine the major product of the substitution reaction shown below:&nbsp;

What nucleophiles would react with 1-iodohexane to form the compounds shown

Benzalkonium bromide is an antiseptic used prior to surgical procedures or 

Consider the following reaction:&nbsp;1-chloro-1,3,4-trimethylcyclopentane 

Suggest an arrow-pushing mechanism for the reaction shown below.

Show which reagents could be used to convert 1-chloropropane into 1-iodopro

Using the given starting material, provide the synthetic pathway to produce

trans-4-chlorocyclohexan-1-ol and cis-4-chlorocyclohexan-1-ol produce diffe

When methyl chloride and sodium iodide are combined equivalently in methano

What is the substitution product for each of the following reactions? Will 

What is the substitution product of the following reactions?(i) (ii) 

A mixture of equal amounts of 2-chloro-2-methylbutane and acetic acid with 

Provide the structures of the missing reagents in the following reactions:

Give the stereoisomer(s) produced by the reaction shown below.

SN2 Reaction

Nucleophilic Substitution

Using Fischer projection, draw the structure for the product formed in the 

Which reactions would occur faster than the remaining one if the nucleophil

The reaction of 2-chlorobutane with sodium methoxide in methanol forms 2-me

What products are formed in the substitution reactions given below? If appl

For the given substitution reaction, what is the product? Show the stereoch

Under which condition will more of (S)-2-methoxypentane be obtained from (S

In the presence of a strong electrophile, the following reaction should hav

How is 1-propanol converted into the compound shown below?

Draw the substitution products for the reactions below (show both stereoiso

An enzyme containing cysteine residues in its active site becomes inactive 

SN1 Reaction

When optically active 2-idopentane is treated with NaI solution, it undergo

Determine the missing molecules in the following reactions:

Propose an SN2 reaction to convert 1-chloropropane into propan-1-ol.

Provide the products that are formed in the given substitution reactions be

Which of the following reactions will proceed at a faster rate?a. CH3Cl + H

Predict the Product

How do we predict if the mechanism is SN1 or SN2?

When given a substitution reaction, use the following two factors to determine the mechanism:

Nucleophile Strength:&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SN1 = &nbsp;&nbsp;WEAK&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SN2 = STRONG

Leaving Group Substitution:&nbsp; &nbsp; SN1 &nbsp;= 3&deg; &gt; 2&deg; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; SN2 = 0&deg; &gt; 1&deg; &gt; 2&deg;

How can we tell which mechanism to use? This question will get more complicated unfortunately, but for now we can use the following factors to answer this question.

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