18. Reactions of Aromatics:EAS and Beyond
Electrophilic Aromatic Substitution
50PRACTICE PROBLEM
The electrophilic aromatic substitution reaction rate for thiophene is greater than that of benzene. It often reacts under mild reaction conditions. Substitution in thiophene occurs preferably at position 2.
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Draw a mechanism for the acetylation of thiophene. You do not have to show steps for generating the CH3C≡O+ ion. You may begin with thiophene and CH3C≡O+ ion.
The electrophilic aromatic substitution reaction rate for thiophene is greater than that of benzene. It often reacts under mild reaction conditions. Substitution in thiophene occurs preferably at position 2.
Draw a mechanism for the acetylation of thiophene. You do not have to show steps for generating the CH3C≡O+ ion. You may begin with thiophene and CH3C≡O+ ion.