18. Reactions of Aromatics:EAS and Beyond
Electrophilic Aromatic Substitution
7PRACTICE PROBLEM
The electrophilic aromatic substitution reaction rate for thiophene is greater than that of benzene. It often reacts under mild reaction conditions. Substitution in thiophene occurs preferably at position 2.
![](https://lightcat-files.s3.amazonaws.com/problem_images/49f8ede2383eadb4-1672331600327.jpg)
Explain why thiophene is more reactive than benzene and why substitution preferably takes place at position 2 than position 3.
The electrophilic aromatic substitution reaction rate for thiophene is greater than that of benzene. It often reacts under mild reaction conditions. Substitution in thiophene occurs preferably at position 2.
Explain why thiophene is more reactive than benzene and why substitution preferably takes place at position 2 than position 3.