Organic Chemistry
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Determine the starting alkyl chloride needed, using Gabriel synthesis, to synthesize hexanamine.
What is the starting alkyl iodide needed, using Gabriel synthesis, to synthesize 3-methylbutanamine?
Show how the following compounds can be prepared using the Gabriel syntheses.
Provide the alkyl bromide needed in a Gabriel synthesis to prepare 2-phenylethanamine.
Draw the alkyl bromide needed in a Gabriel synthesis to prepare cyclopentylmethanamine.
What product will be formed in the reaction shown below?
Why is the Gabriel synthesis more successful with 1-bromopropane compared to 2-bromopropane?
Multiple methods can be used to synthesize primary amines such as reduction of azide and nitro compounds or the Gabriel synthesis. Show how the following amine synthesis can be carried out.
What amino acid is obtained when 2-bromobutane is used in the third step of the N-phthalimidomalonic ester synthesis?