Organic Chemistry
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Determine the product produced of the reaction between 3,5-dimethylpyridine and isobutyl iodide.
Determine the product of the reaction given below.
The antitumor agent triaziquone can cross-link with DNA. Explain why it can form cross-links with DNA.
Suggest a plausible mechanism for the formation of the following quaternary ammonium salt.
Determine the products of the reaction between PhCH2CH2Br and excessive amount of NH3.
Rank the following set of compounds from least to most basic.
Rank the following set of compounds from the least to the most basic.
Rank the indicated nitrogens within each structure from the least to the most basic.
For the structure shown below, rank the indicated nitrogens from the least to the most basic.
Determine the stronger base in each pair of compounds shown below. Provide a brief explanation for your answer.(i) CH3CH2CH(OH)NH2 or CH3CH2CH2NH2(ii) PhNHCH3 or PhCH2NHCH3
In each of the following sets, arrange the compounds in increasing order of their boiling points.
a. dimethyl amine, trimethyl amine, diethyl amineb. diethyl amine, dimethyl amine, dipropyl aminec. methyl amine, methyl alcohol, methyl chloride
The reaction between ammonia and alkyl halides produces a low yield of a primary amine. Explain.
What is the product of the reaction shown below?
Provide a reaction scheme showing the conversion of valine to the compounds listed below. Give the structures of the products.
(i) phenethoxycarbonyl valine
(ii) propoxycarbonyl valine
2-Acetamidophenol is an isomer of acetaminophen that possesses anti-inflammatory properties. Show how you would synthesize 2-acetamidophenol from phenol.
Rank the indicated nitrogens within each structure in order of increasing basicity.
(i) (ii)
Select the stronger base in each pair of compounds. Explain your choice.
True or False. Guanidine is as strong a base as a hydroxide ion. It is a much stronger base than most other amines because of the resonance stabilization of its anion form.
N,N,2,4,6-pentamethylaniline is a stronger base than N,N,4-trimethylaniline. Why?
When one equivalent of ammonia is added to 1-bromopentane, the product is a mixture of pentan-1-amine, dialkylamine, trialkylamine, and some tetraalkylammonium bromide.
(i) Provide a mechanism (up to the dialkylamine stage) to demonstrate how this reaction occurs.
(ii) What changes should be made to obtain a higher yield of pentan-1-amine?
Order these compounds based on increasing base strength.
Arrange the following amines in decreasing order of basicity
Suggest a one-step method to synthesize each of the following compounds:
A compound's basicity depends on its lone pair's availability to bond to a proton. Based on structural effects, arrange the following amines in order of increasing basicity.
Explain why 1-(4-aminophenyl)ethanone is a much weaker base than aniline.
Identify the product of the reaction shown below:
Propose the plausible synthesis of the given compound. The starting molecule must contain no more than 6 carbon atoms.
Draw the plausible synthesis of the given compound. The starting molecule must contain no more than 6 carbon atoms.