22. Carboxylic Acid Derivatives: NAS
Nucleophilic Acyl Substitution
8:05 minutes
Problem 15
Textbook Question
Textbook QuestionWe saw that acid anhydrides react with alcohols, water, and amines. In which of these reactions can the tetrahedral intermediate eliminate the carboxylate ion even if it does not lose a proton before the elimination step? Explain.
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