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Multiple Choice
What is the relationship between these two molecules?
A
Enantiomers
B
Meso
C
Diastereomers
D
Constitutional isomers
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1
Identify the chiral centers in each molecule. Both molecules have two chiral centers, which are the carbon atoms bonded to the NH2 and OH groups.
Determine the configuration (R or S) of each chiral center in both molecules. Use the Cahn-Ingold-Prelog priority rules to assign priorities to the substituents around each chiral center.
Compare the configurations of the corresponding chiral centers in the two molecules. If all chiral centers have opposite configurations, the molecules are enantiomers. If some but not all chiral centers have opposite configurations, they are diastereomers.
Check for symmetry in the molecules. If a molecule has an internal plane of symmetry, it may be a meso compound, which is achiral despite having chiral centers.
Consider the connectivity of atoms. If the connectivity is different, the molecules are constitutional isomers. In this case, the connectivity is the same, so they are not constitutional isomers.