22. Carboxylic Acid Derivatives: NAS
Lactones, Lactams and Cyclization Reactions
5:13 minutes
Problem 21-12
Textbook Question
Textbook QuestionWhen ethyl 4-hydroxybutyrate is heated in the presence of a trace of a basic catalyst (sodium acetate), one of the products is a lactone. Propose a mechanism for formation of this lactone.
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