Hi, everyone. Welcome to the microbiology channel in Pearson Plus. My name is Jason, and I'm an experienced biologist and science educator. My job is to help you learn and understand the content in this course to prepare you for your exams, while also having some fun along the way. I have a master's degree in applied molecular biology and diverse career experiences, including genetics research at Johns Hopkins University and many years of teaching as both a college professor and a professional tutor. In this microbiology video-based course, we'll explore some of the most commonly taught topics, including prokaryotic and eukaryotic cell structure and function, dynamics and control of microbial growth, microbial genetics and metabolism, viruses, the immune system, and much, much more. We've strategically developed this course with you in mind to maximize your learning. Our video content is highly engaging and can be adapted to your class textbook. We have dozens of effective memory tools and mnemonics to help you remember critical information for your test. Also, every video has a downloadable lesson worksheet for you to print off, allowing you to follow along as you watch. There's simply no better way for you to learn and prepare for your exams. If you have any questions along the way, post them in the comments section of any video, and our team will get right back to you. So again, welcome to the microbiology channel in Pearson Plus. We're super excited to have you here. So once you're all ready, let's get started.
- 1. Introduction to Microbiology3h 21m
- Introduction to Microbiology16m
- Introduction to Taxonomy26m
- Scientific Naming of Organisms9m
- Members of the Bacterial World10m
- Introduction to Bacteria9m
- Introduction to Archaea10m
- Introduction to Eukarya20m
- Acellular Infectious Agents: Viruses, Viroids & Prions19m
- Importance of Microorganisms20m
- Scientific Method27m
- Experimental Design30m
- 2. Disproving Spontaneous Generation1h 18m
- 3. Chemical Principles of Microbiology3h 38m
- 4. Water1h 28m
- 5. Molecules of Microbiology2h 23m
- 6. Cell Membrane & Transport3h 28m
- Cell Envelope & Biological Membranes12m
- Bacterial & Eukaryotic Cell Membranes8m
- Archaeal Cell Membranes18m
- Types of Membrane Proteins8m
- Concentration Gradients and Diffusion9m
- Introduction to Membrane Transport14m
- Passive vs. Active Transport13m
- Osmosis33m
- Simple and Facilitated Diffusion17m
- Active Transport30m
- ABC Transporters11m
- Group Translocation7m
- Types of Small Molecule Transport Review9m
- Endocytosis and Exocytosis15m
- 7. Prokaryotic Cell Structures & Functions5h 52m
- Prokaryotic & Eukaryotic Cells26m
- Binary Fission11m
- Generation Times16m
- Bacterial Cell Morphology & Arrangements35m
- Overview of Prokaryotic Cell Structure10m
- Introduction to Bacterial Cell Walls26m
- Gram-Positive Cell Walls11m
- Gram-Negative Cell Walls20m
- Gram-Positive vs. Gram-Negative Cell Walls11m
- The Glycocalyx: Capsules & Slime Layers12m
- Introduction to Biofilms6m
- Pili18m
- Fimbriae & Hami7m
- Introduction to Prokaryotic Flagella12m
- Prokaryotic Flagellar Structure18m
- Prokaryotic Flagellar Movement11m
- Proton Motive Force Drives Flagellar Motility5m
- Chemotaxis14m
- Review of Prokaryotic Surface Structures8m
- Prokaryotic Ribosomes16m
- Introduction to Bacterial Plasmids13m
- Cell Inclusions9m
- Endospores16m
- Sporulation5m
- Germination5m
- 8. Eukaryotic Cell Structures & Functions2h 18m
- 9. Microscopes2h 46m
- Introduction to Microscopes8m
- Magnification, Resolution, & Contrast10m
- Introduction to Light Microscopy5m
- Light Microscopy: Bright-Field Microscopes23m
- Light Microscopes that Increase Contrast16m
- Light Microscopes that Detect Fluorescence16m
- Electron Microscopes14m
- Reviewing the Different Types of Microscopes10m
- Introduction to Staining5m
- Simple Staining14m
- Differential Staining6m
- Other Types of Staining11m
- Reviewing the Types of Staining8m
- Gram Stain13m
- 10. Dynamics of Microbial Growth4h 36m
- Biofilms16m
- Growing a Pure Culture5m
- Microbial Growth Curves in a Closed System21m
- Temperature Requirements for Microbial Growth18m
- Oxygen Requirements for Microbial Growth22m
- pH Requirements for Microbial Growth8m
- Osmolarity Factors for Microbial Growth14m
- Reviewing the Environmental Factors of Microbial Growth12m
- Nutritional Factors of Microbial Growth30m
- Growth Factors4m
- Introduction to Cultivating Microbial Growth5m
- Types of Solid Culture Media4m
- Plating Methods16m
- Measuring Growth by Direct Cell Counts9m
- Measuring Growth by Plate Counts14m
- Measuring Growth by Membrane Filtration6m
- Measuring Growth by Biomass15m
- Introduction to the Types of Culture Media5m
- Chemically Defined Media3m
- Complex Media4m
- Selective Media5m
- Differential Media9m
- Reducing Media4m
- Enrichment Media7m
- Reviewing the Types of Culture Media8m
- 11. Controlling Microbial Growth4h 10m
- Introduction to Controlling Microbial Growth29m
- Selecting a Method to Control Microbial Growth44m
- Physical Methods to Control Microbial Growth49m
- Review of Physical Methods to Control Microbial Growth7m
- Chemical Methods to Control Microbial Growth16m
- Chemicals Used to Control Microbial Growth6m
- Liquid Chemicals: Alcohols, Aldehydes, & Biguanides15m
- Liquid Chemicals: Halogens12m
- Liquid Chemicals: Surface-Active Agents17m
- Other Types of Liquid Chemicals14m
- Chemical Gases: Ethylene Oxide, Ozone, & Formaldehyde13m
- Review of Chemicals Used to Control Microbial Growth11m
- Chemical Preservation of Perishable Products10m
- 12. Microbial Metabolism5h 16m
- Introduction to Energy15m
- Laws of Thermodynamics15m
- Chemical Reactions9m
- ATP20m
- Enzymes14m
- Enzyme Activation Energy9m
- Enzyme Binding Factors9m
- Enzyme Inhibition10m
- Introduction to Metabolism8m
- Negative & Positive Feedback7m
- Redox Reactions22m
- Introduction to Aerobic Cellular Respiration25m
- Types of Phosphorylation12m
- Glycolysis19m
- Entner-Doudoroff Pathway11m
- Pentose-Phosphate Pathway10m
- Pyruvate Oxidation8m
- Krebs Cycle16m
- Electron Transport Chain19m
- Chemiosmosis7m
- Review of Aerobic Cellular Respiration19m
- Fermentation & Anaerobic Respiration23m
- 13. Photosynthesis2h 31m
- 14. DNA Replication2h 25m
- 15. Central Dogma & Gene Regulation7h 14m
- Central Dogma7m
- Introduction to Transcription20m
- Steps of Transcription22m
- Transcription Termination in Prokaryotes7m
- Eukaryotic RNA Processing and Splicing20m
- Introduction to Types of RNA9m
- Genetic Code25m
- Introduction to Translation30m
- Steps of Translation23m
- Review of Transcription vs. Translation12m
- Prokaryotic Gene Expression21m
- Review of Prokaryotic vs. Eukaryotic Gene Expression13m
- Introduction to Regulation of Gene Expression13m
- Prokaryotic Gene Regulation via Operons27m
- The Lac Operon21m
- Glucose's Impact on Lac Operon25m
- The Trp Operon20m
- Review of the Lac Operon & Trp Operon11m
- Introduction to Eukaryotic Gene Regulation9m
- Eukaryotic Chromatin Modifications16m
- Eukaryotic Transcriptional Control22m
- Eukaryotic Post-Transcriptional Regulation28m
- Post-Translational Modification6m
- Eukaryotic Post-Translational Regulation13m
- 16. Microbial Genetics4h 44m
- Introduction to Microbial Genetics11m
- Introduction to Mutations20m
- Methods of Inducing Mutations15m
- Prototrophs vs. Auxotrophs13m
- Mutant Detection25m
- The Ames Test14m
- Introduction to DNA Repair5m
- DNA Repair Mechanisms37m
- Horizontal Gene Transfer18m
- Bacterial Transformation11m
- Transduction32m
- Introduction to Conjugation6m
- Conjugation: F Plasmids18m
- Conjugation: Hfr & F' Cells19m
- Genome Variability21m
- CRISPR CAS11m
- 17. Biotechnology3h 0m
- 18. Viruses, Viroids, & Prions4h 56m
- Introduction to Viruses20m
- Introduction to Bacteriophage Infections14m
- Bacteriophage: Lytic Phage Infections12m
- Bacteriophage: Lysogenic Phage Infections17m
- Bacteriophage: Filamentous Phage Infections8m
- Plaque Assays9m
- Introduction to Animal Virus Infections10m
- Animal Viruses: 1. Attachment to the Host Cell7m
- Animal Viruses: 2. Entry & Uncoating in the Host Cell19m
- Animal Viruses: 3. Synthesis & Replication22m
- Animal Viruses: DNA Virus Synthesis & Replication14m
- Animal Viruses: RNA Virus Synthesis & Replication22m
- Animal Viruses: Antigenic Drift vs. Antigenic Shift9m
- Animal Viruses: Reverse-Transcribing Virus Synthesis & Replication9m
- Animal Viruses: 4. Assembly Inside Host Cell8m
- Animal Viruses: 5. Release from Host Cell15m
- Acute vs. Persistent Viral Infections25m
- COVID-19 (SARS-CoV-2)14m
- Plant Viruses12m
- Viroids6m
- Prions13m
- 19. Innate Immunity7h 15m
- Introduction to Immunity8m
- Introduction to Innate Immunity17m
- Introduction to First-Line Defenses5m
- Physical Barriers in First-Line Defenses: Skin13m
- Physical Barriers in First-Line Defenses: Mucous Membrane9m
- First-Line Defenses: Chemical Barriers24m
- First-Line Defenses: Normal Microflora5m
- Introduction to Cells of the Immune System15m
- Cells of the Immune System: Granulocytes29m
- Cells of the Immune System: Agranulocytes25m
- Introduction to Cell Communication5m
- Cell Communication: Surface Receptors & Adhesion Molecules16m
- Cell Communication: Cytokines27m
- Pattern Recognition Receptors (PRRs)45m
- Introduction to the Complement System24m
- Activation Pathways of the Complement System23m
- Effects of the Complement System23m
- Review of the Complement System12m
- Phagoctytosis21m
- Introduction to Inflammation18m
- Steps of the Inflammatory Response26m
- Fever8m
- Interferon Response25m
- 20. Adaptive Immunity7h 14m
- Introduction to Adaptive Immunity32m
- Antigens12m
- Introduction to T Lymphocytes38m
- Major Histocompatibility Complex Molecules20m
- Activation of T Lymphocytes21m
- Functions of T Lymphocytes25m
- Review of Cytotoxic vs Helper T Cells13m
- Introduction to B Lymphocytes27m
- Antibodies14m
- Classes of Antibodies35m
- Outcomes of Antibody Binding to Antigen15m
- T Dependent & T Independent Antigens21m
- Clonal Selection20m
- Antibody Class Switching17m
- Affinity Maturation14m
- Primary and Secondary Response of Adaptive Immunity21m
- Immune Tolerance28m
- Regulatory T Cells10m
- Natural Killer Cells16m
- Review of Adaptive Immunity25m
- 21. Principles of Disease6h 57m
- Symbiotic Relationships12m
- The Human Microbiome46m
- Characteristics of Infectious Disease47m
- Stages of Infectious Disease Progression26m
- Koch's Postulates26m
- Molecular Koch's Postulates11m
- Bacterial Pathogenesis36m
- Introduction to Pathogenic Toxins6m
- Exotoxins Cause Damage to the Host40m
- Endotoxin Causes Damage to the Host13m
- Exotoxins vs. Endotoxin Review13m
- Immune Response Damage to the Host15m
- Introduction to Avoiding Host Defense Mechanisms8m
- 1) Hide Within Host Cells5m
- 2) Avoiding Phagocytosis31m
- 3) Surviving Inside Phagocytic Cells10m
- 4) Avoiding Complement System9m
- 5) Avoiding Antibodies25m
- Viruses Evade the Immune Response27m
Introduction to Microbiology - Online Tutor, Practice Problems & Exam Prep
Microbiology is the scientific study of microbes, which are organisms too small to be seen without a microscope. The term "micro" means small, while "biology" refers to the study of life. Microbiologists study both living microorganisms, like bacteria and protozoa, and nonliving infectious agents, such as viruses. Key figures in microbiology include Robert Hooke, who first visualized microorganisms, and Antony van Leeuwenhoek, who discovered various microbes in lake water. Understanding these concepts is essential for exploring the microbial world and its impact on life.
Introduction to Microbiology Channel
Video transcript
Introduction to Microbiology
Video transcript
Hey there. Welcome to Clutch Prep Microbiology. My name is Jason, and I'll be your instructor throughout this course. If you have any questions about the content in our videos, feel free to post your questions in the comment section of the video, and one of our tutors will get back to you as soon as possible. Now that being said, let's go on and get started with our introduction to microbiology. Microbiology can be defined as the scientific study of microbes, which are organisms and infectious agents that are simply too small to be seen by the naked eye alone. In the field of microbiology, in order to study these really, really small microbes, we need to use microscopes to allow us to study them. Later in our course, we'll talk a lot more about microscopes, but for now, we're going to focus more on this term microbiology. The term microbiology can actually be defined simply by looking at its roots. Notice that the prefix micro, which is a prefix found in microbiology, means small, and so in the field of microbiology, the main focus is really really small organisms and infectious agents. The word biology means the scientific study of life. The main focus of microbiologists is to study living organisms that are simply really really small. It's also important to note that although microbiologists mainly focus on living organisms that are really really small, they sometimes also study nonliving infectious agents that are really really small. And that's because these nonliving infectious agents like viruses, for example, can infect and affect organisms that are really really small. We'll be able to talk more about this idea as we move forward in our course. It turns out that the smallest and the most basic or the most fundamental unit of life is actually the cell. Moving forward in our course, we're going to talk a lot about the structure of cells and the functions of cells, and we'll also talk about many different types of cells as well. The term organism is a really broad term because the term organism can refer to any individual form of life. The term organism could be referring to a unicellular organism or an organism made of only 1 single cell, or the term organism could be referring to a multicellular organism that is made up of multiple cells. The term microorganism again has that root or that prefix micro, which we already said is a prefix that means small. Microorganism is simply an organism, a living organism, that is simply too small to be seen with the naked eye alone. Once again, we need the aid of microscopes in order to visualize and study these microorganisms, these organisms that are really really small. Notice that down below we're also defining microbes again for a second time, even though we technically already defined it up above. The reason for that is because sometimes the term microorganism is used in a synonymous way to the word microbes. However, technically, these are not synonyms. Microorganism and microbes have subtle differences in their definitions. Here we put these two definitions side by side to help you better understand how these two terms are similar, but also how they are different. Once again, microorganisms is referring to living organisms that are really, really small. The term microbes includes microorganisms. So it also refers to living organisms that are really really small. However, the term microbes also is referring to nonliving infectious agents such as viruses for example that are also too small to be seen by the naked eye. And so, microbes, includes microorganisms, but it also includes nonliving infectious agents. Whereas the term microorganisms only is referring to living organisms, but does not refer to nonliving infectious agents. Hopefully that can help you better understand the differences between those two key terms. If we take a look at our image down below, notice on the left hand side, we're showing you a human being, a microbiologist if you will, which is a living organism of course. More specifically, this human is going to be a multicellular organism because humans are made up of many cells, 1,000,000,000,000 and 1,000,000,000,000 of cells. Notice that this microbiologist, in order to study microbes which are really really small, needs to use a microscope. Again, we'll talk a lot more about microscopes later in our course. But the microscopes allow the scientists to visualize the microbes, which are really really small. Once again, the term microbes is going to include really really small microorganisms, living microorganisms, such as bacterium that you can see right here. This is one single celled bacteria. And, microbes also include some nonliving infectious agents, such as viruses, for example, which are lacking many of the characteristics of life and so are generally not considered alive. But they are nonliving infectious agents, and sometimes they are still studied by microbiologists because these nonliving infectious agents can sometimes affect cells, living microorganisms. And so over here on the right hand side, we're showing you a collage here of many different images of the microbial world, all of the microbes that exist such as viruses and, specific type of archaea and, virus, other viruses and bacteria, and single-celled organisms, and these are called bacteriophages. And so we'll talk a lot about the microbial world, basically the different types of microbes, microorganisms, and nonliving infectious agents as we move forward in our course. But for now, this here concludes our introduction to microbiology. And again, we'll be able to learn a lot more as we move forward. So I'll see you all in our next video.
Which of these is considered a microbe but NOT a microorganism?
Which of these are characteristics of microorganisms?
Discovering Microorganisms
Video transcript
In this video, we're going to focus on the discovery of microorganisms. It turns out that humans were not always aware that microorganisms even existed, let alone that they exist in pretty much every conceivable environment around us. The existence of microorganisms was actually discovered just a couple of hundred years ago during the time period between 1665 and 1674.
In 1665, an English microscopist named Robert Hooke was actually the very first person to visualize and depict or create a drawing of a microorganism. More specifically, Robert Hooke described a common bread mold known as mucore as a microscopical mushroom. If you take a look at the image down below over here on the left-hand side, there's a little portrait of Robert Hooke, who lived from 1635 to 1703. Here is an image of Hooke's microscope that he used to visualize the very first microorganism and depict the very first microorganism. Over here on the right is Robert Hooke's drawing of the bread mold, his depiction of the bread mold.
Now in 1674, just a few years later, a Dutch merchant named Antony van Leeuwenhoek analyzed a drop of lake water with a microscope and he saw microbes, many different types of microbes other than just these microscopical mushrooms. Antony van Leeuwenhoek described and depicted protozoa, which are very small eukaryotic organisms. We'll talk about them more later in our course. He also depicted bacteria, which are very small prokaryotic organisms. Again, we'll talk more about those later in our course. Antony van Leeuwenhoek depicted a whole different set of microorganisms and called these microorganisms animalcules, which really just means little animals.
If you take a look at the image down below, you can see a portrait of Antony van Leeuwenhoek, who lived from 1632 to 1723. Here is an image of Antony van Leeuwenhoek’s microscope that he used to visualize the protozoa and bacteria. Here is an image of the depictions that Antony van Leeuwenhoek created when he observed that lake water. Again, he called them animalcules or little animals, and you can see that there are many different types of protozoa and bacteria that he had drawn in his images.
While Robert Hooke observed a microscopical mushroom, a common bread mold, which is a little bit larger than these other protozoa and bacteria were, they are still at the microscopic scale. Both deserve equal credit for revealing the microbial world. Due to Robert Hooke and Antony van Leeuwenhoek's discoveries, they revealed that there was a microbial world of really small organisms and infectious agents that were all around us.
This concludes our lesson on discovering microorganisms, and we'll be able to get some practice applying these concepts as we move forward in our course. So, I'll see you all in our next video.
Antonie van Leeuwenhoek observed microorganisms under his microscope and called them 'animalicules' (little animals). Which microorganisms did he observe?
Robert Hook's and Antonie van Leeuwenhoek's microscopes were not powerful enough to observe:
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What is microbiology and why is it important?
Microbiology is the scientific study of microbes, which are organisms and infectious agents too small to be seen with the naked eye. This field is crucial because it helps us understand the roles these tiny entities play in various environments, including human health, agriculture, and industry. Microbiologists study both living microorganisms, like bacteria and protozoa, and nonliving infectious agents, such as viruses. Understanding microbiology is essential for developing antibiotics, vaccines, and other medical treatments, as well as for advancing biotechnology and environmental science.
Who were Robert Hooke and Antony van Leeuwenhoek, and what were their contributions to microbiology?
Robert Hooke and Antony van Leeuwenhoek were pioneers in the field of microbiology. Robert Hooke, an English microscopist, was the first to visualize and depict a microorganism in 1665, specifically a common bread mold. Antony van Leeuwenhoek, a Dutch merchant, discovered various microbes in lake water in 1674, including protozoa and bacteria. He called these microorganisms 'animalcules,' meaning little animals. Their discoveries revealed the existence of a microbial world, laying the foundation for modern microbiology.
What are the differences between microorganisms and microbes?
While the terms 'microorganisms' and 'microbes' are often used interchangeably, they have subtle differences. Microorganisms refer specifically to living organisms that are too small to be seen with the naked eye, such as bacteria, protozoa, and fungi. On the other hand, microbes include both living microorganisms and nonliving infectious agents like viruses. Therefore, all microorganisms are microbes, but not all microbes are microorganisms.
Why do microbiologists use microscopes, and what can they study with them?
Microbiologists use microscopes because microbes are too small to be seen with the naked eye. Microscopes allow scientists to visualize and study these tiny entities in detail. With microscopes, microbiologists can examine the structure and function of various microorganisms, such as bacteria, protozoa, and fungi, as well as nonliving infectious agents like viruses. This detailed study is essential for understanding microbial behavior, interactions, and their impact on larger biological systems.
What is the significance of the cell in microbiology?
The cell is the smallest and most fundamental unit of life, making it a central focus in microbiology. Understanding cell structure and function is crucial for studying microorganisms, which can be unicellular (single-celled) or multicellular (composed of multiple cells). By examining cells, microbiologists can gain insights into how microorganisms grow, reproduce, and interact with their environments, which is essential for developing medical treatments, understanding disease mechanisms, and advancing biotechnological applications.
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