In this video, we're going to continue to talk about light microscopes that detect fluorescence by talking about confocal scanning laser microscopes or CSLMs. These confocal scanning laser microscopes or CSLMs are computer-controlled microscopes that couple a laser to a fluorescence microscope. The laser portion is responsible for generating high contrast, three-dimensional (3D) images that allow the viewer to access several different planes of focus inside of the specimen. This can be used to look inside of cells at different layers of the cell.

If we take a look at our image down below, we can get a better understanding of these confocal scanning laser microscopes. Over here on the left, notice that we're showing you that this is a complex device that is going to be controlled by a computer, and it links a laser to a fluorescence microscope. These are abbreviated as CSLMs for confocal scanning laser microscope.

Now over here, on the right, we're showing you some of the images that can be created. This is looking at different planes or different levels of the specimen. Over here on the left, we're showing you this Philampelanchi ramosa seed coat. This is showing you Arabidopsis thaliana cells, and here it's showing you rat pancreas cells. This is another form of being able to detect fluorescence using these CSLMs.

Once again, we'll be able to get some practice applying these concepts as we move forward. So I'll see you all in our next video.