In this example question, it says, "Identify all the statements that are not true about gluconeogenesis." So, option A states, "Gluconeogenesis is the exact reverse of the glycolysis pathway." This statement is not true. It is not the exact reverse; there are some exceptions that occur. That's why this is not true. It is not an exact opposite or reverse, as there are some exceptions.
Gluconeogenesis primarily occurs in the liver cells. That is true. It is most active in times of fasting or starvation. This is also true. When your blood glucose levels are low, this process will kickstart the synthesis of glucose through gluconeogenesis.
Certain non-carbohydrates have to be converted to pyruvate before entering the gluconeogenesis pathway. Yes, certain non-carbohydrates, such as lactate and amino acids, must be converted into pyruvate, from pyruvate to dihydroxyacetone phosphate (DHAP) before they can eventually become glucose. So this last statement is true.
Out of our four statements, only option A is an incorrect or false statement. Here, gluconeogenesis is not the exact reverse of the glycolysis pathway, as it is the reverse with some exceptions that exist.