In this video, we're going to take a look at basic hydrolysis of amides. Now, under this reaction, we're going to say that the hydroxide ion, which is OH-, dissolved in water reacts with an amide. The reaction cleaves or cuts the amide bond to create a carboxylate anion and an amine. Now, if we take a look here at this general reaction, we're going to cut this amide bond by using aqueous hydroxide. So that just means it's dissolved in water and accompanied by some heat.
So essentially, what happens here is that the carbonyl carbon will gain an O- because a carboxylate anion is just the conjugate base form of a carboxylic acid. So instead of having an OH group, it has an O minus group. And the nitrogen here would only gain 1 hydrogen atom. Here we create a neutral amine. So under basic conditions, we're not making a carboxylic acid, we're making its conjugate base, which is our carboxylate anion. And for the amine, it's going to be a neutral amine that's being formed.