17. Mutation, Repair, and Recombination
Induced Mutations
17. Mutation, Repair, and Recombination
Induced Mutations - Video Tutorials & Practice Problems
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Induced Mutations
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Problem
ProblemWhich of the following mutagens wedges between DNA bases to disrupt the helix structure?
A
Base analogs
B
Alylating agents
C
Intercalating agents
D
UV light
3
Problem
ProblemWhich of the following mutagens alters base affinities by adding an alkyl group?
A
Base analogs
B
Alylating agents
C
Intercalating agents
D
UV light
4
Problem
ProblemWhich of the following mutations would have the least effect on an individual?
A
4 base pair insertion in an intron
B
Deletion of an exon
C
A nonsense mutation in the last exon of a gene
D
A point mutation in the splice site of an intron
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PRACTICE PROBLEMS AND ACTIVITIES (37)
- Identify two general ways chemical mutagens can alter DNA. Give examples of these two mechanisms.
- In this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we ...
- In this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we ...
- Nitrous acid and 5-bromodeoxyuracil (BrdU) alter DNA by different mechanisms. What type of mutation does each ...
- UV irradiation causes damage to bacterial DNA. What kind of damage is frequently caused and how does photolyas...
- In March 2011 an earthquake measuring approximately 9.0 on the Richter scale struck Fukushima, Japan. Several ...
- In March 2011 an earthquake measuring approximately 9.0 on the Richter scale struck Fukushima, Japan. Several ...
- Ultraviolet (UV) radiation is mutagenic.Identify and describe two DNA repair mechanisms that remove UV-induced...
- Ultraviolet (UV) radiation is mutagenic.How do UV-induced DNA lesions lead to mutation?
- Ultraviolet (UV) radiation is mutagenic.What kind of DNA lesion does UV energy cause?
- Researchers interested in studying mutation and mutation repair often induce mutations with various agents. Wh...
- Researchers interested in studying mutation and mutation repair often induce mutations with various agents. Wh...
- Discuss the advantages (and possible disadvantages) of the different mutagens in Table 14.1.
- Contrast and compare the mutagenic effects of deaminating agents, alkylating agents, and base analogs.
- Describe how the Ames test screens for potential environmental mutagens. Why is it thought that a compound tha...
- In 2013 the actress Angelina Jolie elected to have prophylactic double-mastectomy surgery to prevent breast ca...
- Xeroderma pigmentosum (XP) is an autosomal recessive condition characterized by moderate to severe sensitivity...
- In 2010, a U.S. District Judge ruled to invalidate Myriad Genetics' patents on the BRCA1 and BRCA2 genes. Judg...
- In 2010, a U.S. District Judge ruled to invalidate Myriad Genetics' patents on the BRCA1 and BRCA2 genes. Judg...
- Following the spill of a mixture of chemicals into a small pond, bacteria from the pond are tested and show an...
- In an Ames test using his⁻ Salmonella bacteria a researcher determines that adding a test compound plus the S9...
- In an Ames test using his⁻ Salmonella bacteria a researcher determines that adding a test compound plus the S9...
- A wild-type culture of haploid yeast is exposed to ethyl methanesulfonate (EMS). Yeast cells are plated on a c...
- A wild-type culture of haploid yeast is exposed to ethyl methanesulfonate (EMS). Yeast cells are plated on a c...
- A wild-type culture of haploid yeast is exposed to ethyl methanesulfonate (EMS). Yeast cells are plated on a c...
- A fragment of a wild-type polypeptide is sequenced for seven amino acids. The same polypeptide region is seque...
- A fragment of a wild-type polypeptide is sequenced for seven amino acids. The same polypeptide region is seque...
- A fragment of a wild-type polypeptide is sequenced for seven amino acids. The same polypeptide region is seque...
- Experiments by Charles Yanofsky in the 1950s and 1960s helped characterize the nature of tryptophan synthesis ...
- Alkaptonuria is a human autosomal recessive disorder caused by mutation of the HAO gene that encodes the enzym...
- Using your knowledge of DNA repair pathways, choose the pathway that would be used to repair the following typ...
- Using your knowledge of DNA repair pathways, choose the pathway that would be used to repair the following typ...
- Using your knowledge of DNA repair pathways, choose the pathway that would be used to repair the following typ...
- Using your knowledge of DNA repair pathways, choose the pathway that would be used to repair the following typ...
- Common baker's yeast (Saccharomyces cerevisiae) is normally grown at 37°C, but it will grow actively at temper...
- Common baker's yeast (Saccharomyces cerevisiae) is normally grown at 37°C, but it will grow actively at temper...
- Common baker's yeast (Saccharomyces cerevisiae) is normally grown at 37°C, but it will grow actively at temper...