rett-syndrome-caused-by-mutations-in-the-mecp2-gene-follows-an-x-linked-dominant

Question

Rett syndrome is caused by mutations in the MECP2 gene and follows an X-linked dominant pattern of inheritance. Which of the following statements is therefore true?

Accepted Answer

Once one allele is defective, the condition is expressed phenotypically.

Answer

It takes two defective alleles for the condition to be phenotypically expressed in females.

Answer

It only affects females.

Answer

The trait will skip in one generation.

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Rett syndrome is caused by mutations in the MECP2 gene and follows an X-linked dominant pattern of inheritance. Which of the following statements is therefore true?