Mapping with Markers
4. Genetic Mapping and Linkage / Mapping with Markers / Problem 2
An autosomal recessive disorder with alleles A and a has been linked to a VNTR. The recombination frequency of the disease gene and the VNTR is 10.7%. The accompanying pedigree shows a two-generation family in which the disease is present. The VNTR has two alleles V1 and V2 and the gel electrophoresis pattern of each family member has been shown below.
![Pedigree chart showing two generations of a family with an autosomal recessive disorder.](https://lightcat-files.s3.amazonaws.com/problem_images/a78d086f287f0660-1678913638519.jpg)
![Gel electrophoresis pattern displaying VNTR alleles V1 and V2 for family members.](https://lightcat-files.s3.amazonaws.com/problem_images/8436fc4f9c3c0241-1678911343402.jpg)
Based on this information, identify the genotype of II-5 for the disease gene.
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