4. Genetic Mapping and Linkage - Part 2 of 2
4. Genetic Mapping and Linkage / Mapping with Markers / Problem 8
An autosomal recessive disorder with alleles A and a has been linked to a VNTR. The recombination frequency of the disease gene and the VNTR is 10.7%. The accompanying pedigree shows a two-generation family in which the disease is present. The VNTR has two alleles V1 and V2 and the gel electrophoresis pattern of each family member has been shown.
![Pedigree chart showing two generations of a family with an autosomal recessive disorder.](https://lightcat-files.s3.amazonaws.com/problem_images/e3d5fd7275dfd812-1678912959868.jpg)
![Gel electrophoresis pattern displaying VNTR alleles V1 and V2 for family members II-2, II-3, and II-5.](https://lightcat-files.s3.amazonaws.com/problem_images/f816a95afdec0135-1678912970589.jpg)
Based on this information, identify the syntenic disease gene and VNTR alleles in II-2, II-3 and II-5.
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