4. Genetic Mapping and Linkage
Mapping with Markers
4. Genetic Mapping and Linkage
Mapping with Markers: Study with Video Lessons, Practice Problems & Examples
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4PRACTICE PROBLEM
An autosomal recessive disorder with alleles A and a has been linked to a VNTR. The recombination frequency of the disease gene and the VNTR is 10.7%. The accompanying pedigree shows a two-generation family in which the disease is present. The VNTR has two alleles V1 and V2 and the gel electrophoresis pattern of each family member has been shown.
Based on this information, identify the syntenic disease gene and VNTR alleles in II-2, II-3 and II-5.
An autosomal recessive disorder with alleles A and a has been linked to a VNTR. The recombination frequency of the disease gene and the VNTR is 10.7%. The accompanying pedigree shows a two-generation family in which the disease is present. The VNTR has two alleles V1 and V2 and the gel electrophoresis pattern of each family member has been shown.
Based on this information, identify the syntenic disease gene and VNTR alleles in II-2, II-3 and II-5.