Table of contents
- 1. Introduction to Genetics(0)
- 2. Mendel's Laws of Inheritance(0)
- 3. Extensions to Mendelian Inheritance(0)
- 4. Genetic Mapping and Linkage(0)
- 5. Genetics of Bacteria and Viruses(0)
- 6. Chromosomal Variation(0)
- 7. DNA and Chromosome Structure(0)
- 8. DNA Replication(0)
- 9. Mitosis and Meiosis(0)
- 10. Transcription(0)
- 11. Translation(0)
- 12. Gene Regulation in Prokaryotes(0)
- 13. Gene Regulation in Eukaryotes(0)
- 14. Genetic Control of Development(0)
- 15. Genomes and Genomics(0)
- 16. Transposable Elements(0)
- 17. Mutation, Repair, and Recombination(0)
- 18. Molecular Genetic Tools(0)
- 19. Cancer Genetics(0)
- 20. Quantitative Genetics(0)
- 21. Population Genetics(0)
- 22. Evolutionary Genetics(0)
4. Genetic Mapping and Linkage
Mapping Genes
4. Genetic Mapping and Linkage
Mapping Genes: Study with Video Lessons, Practice Problems & Examples
Back to all problems
11PRACTICE PROBLEM
A geneticist is studying a family with an autosomal dominant disease that has been mapped to chromosome 7. Two DNA markers, A and B, are located on chromosome 7 near the disease locus. The following LOD scores were obtained:
θ = recombination frequency
LOD score
Marker A θ = 0.10 2.1
Marker A θ = 0.20 0.1
Marker B θ = 0.05 1.8
Marker B θ = 0.10 0.4
Based on the LOD scores, which marker is most closely linked to the disease locus?
A geneticist is studying a family with an autosomal dominant disease that has been mapped to chromosome 7. Two DNA markers, A and B, are located on chromosome 7 near the disease locus. The following LOD scores were obtained:
θ = recombination frequency
LOD score
Marker A θ = 0.10 2.1
Marker A θ = 0.20 0.1
Marker B θ = 0.05 1.8
Marker B θ = 0.10 0.4
Based on the LOD scores, which marker is most closely linked to the disease locus?