Table of contents
- 1. Introduction to Genetics(0)
- 2. Mendel's Laws of Inheritance(0)
- 3. Extensions to Mendelian Inheritance(0)
- 4. Genetic Mapping and Linkage(0)
- 5. Genetics of Bacteria and Viruses(0)
- 6. Chromosomal Variation(0)
- 7. DNA and Chromosome Structure(0)
- 8. DNA Replication(0)
- 9. Mitosis and Meiosis(0)
- 10. Transcription(0)
- 11. Translation(0)
- 12. Gene Regulation in Prokaryotes(0)
- 13. Gene Regulation in Eukaryotes(0)
- 14. Genetic Control of Development(0)
- 15. Genomes and Genomics(0)
- 16. Transposable Elements(0)
- 17. Mutation, Repair, and Recombination(0)
- 18. Molecular Genetic Tools(0)
- 19. Cancer Genetics(0)
- 20. Quantitative Genetics(0)
- 21. Population Genetics(0)
- 22. Evolutionary Genetics(0)
14. Genetic Control of Development
Developmental Patterning Genes
14. Genetic Control of Development
Developmental Patterning Genes: Study with Video Lessons, Practice Problems & Examples
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30PRACTICE PROBLEM
During vulva formation in Caenorhabditis elegans, the interaction between two neighboring cells, Z1.ppp and Z4.aaa, determines which will become the gonadal anchor cell (from which the vulva forms) and which will become a precursor to the uterus. The lag-2 gene encodes the Notch signal protein, and the LIN-12 gene encodes the Notch receptor protein. By chance, one cell ends up secreting more of the LAG-2 protein than the other cell, which causes the neighboring cell to increase production of the LIN-12 protein. The expression of LIN-12 directs the selection of the uterine pathway. What will the phenotype be if both cells express excess LIN-12 protein?
During vulva formation in Caenorhabditis elegans, the interaction between two neighboring cells, Z1.ppp and Z4.aaa, determines which will become the gonadal anchor cell (from which the vulva forms) and which will become a precursor to the uterus. The lag-2 gene encodes the Notch signal protein, and the LIN-12 gene encodes the Notch receptor protein. By chance, one cell ends up secreting more of the LAG-2 protein than the other cell, which causes the neighboring cell to increase production of the LIN-12 protein. The expression of LIN-12 directs the selection of the uterine pathway. What will the phenotype be if both cells express excess LIN-12 protein?