Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
2:07 minutes
Problem 10e
Textbook Question
Textbook QuestionThe dorsal pigment pattern of frogs can be either 'leopard' (white pigment between dark spots) or 'mottled' (pigment between spots appears mottled). The trait is controlled by an autosomal gene. Males and females are selected from pure-breeding populations, and a pair of reciprocal crosses is performed. The cross results are shown below.
Cross 1: P₁: Male leopard x male mottled
F₁: All mottled
F₂: 70 mottled, 22 leopard
Cross 2: P₁: Male mottled x female leopard
F₁: All mottled
F₂: 50 mottled, 18 leopard
Propose two different genetic crosses that would allow you to determine the genotype of one mottled frog from the F₂ generation.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Autosomal Inheritance
Autosomal inheritance refers to the transmission of traits controlled by genes located on the autosomes, which are the non-sex chromosomes. In this case, the dorsal pigment pattern of frogs is determined by an autosomal gene, meaning that both males and females can inherit and express the trait. Understanding this concept is crucial for predicting the inheritance patterns and ratios observed in the offspring of genetic crosses.
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Autosomal Pedigrees
Reciprocal Crosses
Reciprocal crosses involve mating individuals of different phenotypes to observe the inheritance of traits. In the provided question, two reciprocal crosses were performed between leopard and mottled frogs, allowing researchers to determine how the traits are passed on through generations. This method helps identify whether a trait is dominant or recessive and provides insight into the genotypes of the parents and offspring.
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Trihybrid Cross
Phenotypic Ratios in F₂ Generation
The F₂ generation results from the self-fertilization or interbreeding of F₁ individuals. The phenotypic ratios observed in the F₂ generation can reveal the underlying genotypes of the parents. In this case, the ratios of mottled to leopard frogs (70:22 and 50:18) suggest a dominant-recessive relationship, which is essential for proposing genetic crosses to determine the genotype of a mottled frog.
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