Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
8. DNA Replication
Telomeres and Telomerase
3:43 minutes
Problem 26b
Textbook Question
Textbook QuestionTelomeres are found at the ends of eukaryotic chromosomes. What is the functional role of telomeres?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Telomeres
Telomeres are repetitive nucleotide sequences located at the ends of eukaryotic chromosomes. They protect the chromosome ends from deterioration and prevent them from fusing with neighboring chromosomes. Each time a cell divides, telomeres shorten, which is associated with aging and cellular senescence.
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Chromosome Stability
The stability of chromosomes is crucial for maintaining genetic integrity during cell division. Telomeres play a vital role in chromosome stability by preventing the loss of essential DNA sequences during replication. This stability is essential for proper cell function and the prevention of genetic disorders.
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Cellular Aging
Cellular aging, or senescence, is the process by which cells lose the ability to divide and function effectively over time. Telomere shortening is a key factor in this process, as critically short telomeres trigger cellular stress responses that lead to growth arrest. Understanding this relationship helps explain the biological mechanisms of aging and age-related diseases.
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