Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Probability and Genetics
2:26 minutes
Problem 39b
Textbook Question
Textbook QuestionA geneticist from an alien planet that prohibits genetic research brought with him to Earth two pure-breeding lines of frogs. One line croaks by uttering 'rib-it rib-it' and has purple eyes. The other line croaks more softly by muttering 'knee-deep knee-deep' and has green eyes. With a newfound freedom of inquiry, the geneticist mated the two types of frogs, producing F₁ frogs that were all utterers and had blue eyes. A large F₂ generation then yielded the following ratios: 27/64 blue-eyed, 'rib-it' utterer 12/64 green-eyed, 'rib-it' utterer 9/64 blue-eyed, 'knee-deep' mutterer 9/64 purple-eyed, 'rib-it' utterer 4/64 green-eyed, 'knee-deep' mutterer 3/64 purple-eyed, 'knee-deep' mutterer One set of crosses with his true-breeding lines initially caused the geneticist some confusion. When he crossed true-breeding purple-eyed, 'knee-deep' mutterers with true-breeding green-eyed, 'knee-deep' mutterers, he often got different results. In some matings, all offspring were blue-eyed, 'knee-deep' mutterers, but in other matings all offspring were purple-eyed, 'knee-deep' mutterers. In still a third mating, 1/2 blue-eyed, 'knee-deep' mutterers and 1/2 purple-eyed, 'knee-deep' mutterers were observed. Explain why the results differed.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations based on the principles established by Gregor Mendel. It involves understanding dominant and recessive alleles, genotype and phenotype relationships, and the segregation and independent assortment of genes during gamete formation. This framework is essential for predicting the outcomes of genetic crosses, such as those described in the frog experiment.
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Descriptive Genetics
Genotype and Phenotype
The genotype refers to the genetic makeup of an organism, while the phenotype is the observable expression of that genotype, influenced by environmental factors. In the frog example, the genotype determines traits like eye color and croaking sound, which manifest as phenotypes. Understanding the relationship between genotype and phenotype is crucial for interpreting the results of the geneticist's crosses.
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Gamete Genotypes
Incomplete Dominance and Codominance
Incomplete dominance and codominance are patterns of inheritance where neither allele is completely dominant over the other. In incomplete dominance, the phenotype of heterozygotes is a blend of the two parental traits, while in codominance, both traits are fully expressed. The varying results in the geneticist's crosses suggest that these inheritance patterns may be at play, leading to different phenotypic ratios in the offspring.
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Variations on Dominance
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