Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Sex-Linked Genes
2:53 minutes
Problem 25d
Textbook Question
Textbook QuestionIn Drosophila, an X-linked recessive mutation, scalloped (sd), causes irregular wing margins. Diagram the F₁ and F₂ results if (a) a scalloped female is crossed with a normal male; (b) a scalloped male is crossed with a normal female. Compare these results with those that would be obtained if the scalloped gene were autosomal.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
X-linked Inheritance
X-linked inheritance refers to the pattern of inheritance for genes located on the X chromosome. In this case, the scalloped (sd) mutation is recessive, meaning that females (XX) need two copies of the mutant allele to express the phenotype, while males (XY) only need one. This results in different phenotypic ratios in male and female offspring depending on the parental genotypes.
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X-Inactivation
Punnett Square
A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross. By organizing the alleles of each parent, it allows for a visual representation of the possible combinations in the F₁ and F₂ generations. This tool is essential for analyzing the inheritance patterns of traits, especially when dealing with sex-linked traits like the scalloped mutation.
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Chi Square Analysis
Autosomal vs. X-linked Genes
Autosomal genes are located on non-sex chromosomes and are inherited equally by both sexes, while X-linked genes are found on the X chromosome and exhibit different inheritance patterns between males and females. If the scalloped gene were autosomal, both sexes would express the phenotype equally if they inherited the recessive allele, leading to different ratios in the offspring compared to the X-linked scenario.
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Sex-Linked Genes
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