Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
21. Population Genetics
Hardy Weinberg
2:36 minutes
Problem 10b
Textbook Question
Textbook QuestionThe ability to taste the bitter compound phenylthiocarbamide (PTC) is an autosomal dominant trait. The inability to taste PTC is a recessive condition. In a sample of 500 people, 360 have the ability to taste PTC and 140 do not. Calculate the frequency of the dominant allele
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Autosomal Dominance and Recessiveness
Autosomal dominance refers to a pattern of inheritance where only one copy of a dominant allele is needed for the trait to be expressed. In contrast, a recessive trait requires two copies of the recessive allele for expression. In this case, the ability to taste PTC is dominant, meaning individuals with at least one dominant allele can taste it, while those with two recessive alleles cannot.
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Variations on Dominance
Hardy-Weinberg Principle
The Hardy-Weinberg principle provides a mathematical framework for understanding allele frequencies in a population at equilibrium. It states that allele and genotype frequencies will remain constant from generation to generation in the absence of evolutionary influences. This principle is essential for calculating allele frequencies, such as the frequency of the dominant allele in the given population.
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Hardy Weinberg
Allele Frequency Calculation
Allele frequency is the proportion of a specific allele among all allele copies in a population. To calculate the frequency of the dominant allele (P) in this scenario, we can use the number of individuals who can taste PTC (360) and the total population (500) to derive the frequencies of both the dominant and recessive alleles, applying the Hardy-Weinberg equations.
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