Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Penetrance and Expressivity
5:43 minutes
Problem 35
Textbook Question
Textbook QuestionContrast penetrance and expressivity as the terms relate to phenotypic expression.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Penetrance
Penetrance refers to the proportion of individuals with a specific genotype that actually express the associated phenotype. It is often expressed as a percentage and indicates whether a trait is observed in individuals carrying the gene. For example, if a genetic condition has 80% penetrance, 80 out of 100 individuals with the genotype will show the phenotype.
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Expressivity
Expressivity describes the degree to which a genotype is expressed in an individual's phenotype. Unlike penetrance, which is a binary measure (expressed or not), expressivity can vary among individuals, leading to a range of phenotypic manifestations. For instance, a genetic disorder may be expressed mildly in some individuals and severely in others, despite having the same genotype.
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Phenotypic Variation
Phenotypic variation refers to the differences in appearance or function among individuals of the same species, which can arise from genetic differences, environmental influences, or interactions between the two. Understanding phenotypic variation is crucial for studying traits influenced by penetrance and expressivity, as it helps explain why individuals with the same genotype may exhibit different phenotypes.
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