Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Pedigrees
1:50 minutes
Problem 21b
Textbook Question
Textbook QuestionConsider the following pedigree. Predict the mode of inheritance of the trait of interest and the most probable genotype of each individual. Assume that the alleles A and a control the expression.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Pedigree Analysis
Pedigree analysis is a method used to trace the inheritance of traits through generations in a family tree. It helps identify patterns of inheritance, such as dominant or recessive traits, by examining the phenotypes of family members. Symbols in a pedigree chart represent individuals, with filled shapes indicating affected individuals and unfilled shapes indicating unaffected ones.
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Modes of Inheritance
Modes of inheritance refer to the patterns by which genetic traits are passed from parents to offspring. The primary modes include autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive. Understanding these modes is crucial for predicting the likelihood of traits appearing in offspring based on parental genotypes.
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Genotype Prediction
Genotype prediction involves determining the genetic makeup of individuals based on observed traits and inheritance patterns. By analyzing the pedigree, one can infer the possible genotypes (AA, Aa, or aa) of individuals based on their phenotypes and the inheritance mode. This prediction is essential for understanding the likelihood of trait expression in future generations.
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