During an examination of the genomic sequences surroundi...

Question

During an examination of the genomic sequences surrounding the human β-globin gene, you discover a region of DNA that bears sequence resemblance to the glucocorticoid response element (GRE) of the human metallothionein IIA (hMTIIA) gene. Describe experiments that you would design to test (1) whether this sequence was necessary for accurate β-globin gene expression and (2) whether this sequence acted in the same way as the hMTIIA gene's GRE.

Accepted Answer

Hi, everybody. Let's take a look at this practice problem together, which of the following core moans promotes the transcription of the human mortality meaning to a gene under stress conditions. Now, metallic diogenes are proteins and they are made under stressful conditions. They are important as antioxidants and control heavy metal concentrations in cells. So let's identify the hormone that promotes their transcription. We've got a oxytocin. Now, oxytocin is a hormone that is produced in the hypothalamus and it is important in reproductive system management. So it's not secreted under stressful conditions. So, a is not the correct answer. Then we've got option B. Glue Coogan. Now, Glue Coogan is a hormone that is secreted from the pancreas and it plays a role in controlling blood sugar levels. It's not released in response to stress. And so B is also not the correct answer. Then we've got D insulin. So like Glue Kogan insulin is created from the pancreas and its purpose is to help cells absorb glucose from the blood. And therefore, D is also not the correct answer. The correct answer is option C glucocorticoids. So these are hormones that are secreted from adrenal glands and when they are secreted, it will bind the, its receptor and cell cytoplasm. This changes its confirmation that allows it to enter into the nucleus and bind to a glucocorticoids response element. Therefore, enhancing M T two A transcription or metallic fi any into a transcription. So the correct answer is c glucocorticoids. Alright. Everyone, I hope you found this helpful and I'll see you soon for the next practice problem.

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