Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
14. Genetic Control of Development
Developmental Patterning Genes
1:47 minutes
Problem 13d
Textbook Question
Textbook QuestionThe Drosophila homeotic mutation spineless aristapedia (ssᵃ) results in the formation of a miniature tarsal structure (normally part of the leg) on the end of the antenna. What insight is provided by (ssᵃ) concerning the role of genes during determination?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Homeotic Genes
Homeotic genes are crucial in determining the identity of body segments during development. They encode transcription factors that regulate the expression of other genes, guiding the formation of specific structures in the correct locations. Mutations in these genes can lead to the transformation of one body part into another, as seen in the Drosophila spineless aristapedia mutation.
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Segmentation Genes
Gene Regulation
Gene regulation refers to the mechanisms that control the expression of genes, determining when and how much of a gene product is made. This process is essential for proper development, as it ensures that genes are activated or silenced at the right times and in the right tissues. The spineless aristapedia mutation illustrates how misregulation can lead to abnormal structures, highlighting the importance of precise gene control.
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Review of Regulation
Morphogenetic Fields
Morphogenetic fields are regions in an embryo where specific developmental processes occur, influenced by signaling molecules and gene expression patterns. These fields guide the formation of structures and their spatial organization. The presence of a tarsal structure on the antenna in the ssᵃ mutation suggests that the morphogenetic field for leg development has been misappropriated, indicating the flexibility and specificity of developmental pathways.
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