What is a quantitative trait locus (QTL)? Suppose you wanted to s...

Question

What is a quantitative trait locus (QTL)? Suppose you wanted to search for QTLs influencing fruit size in tomatoes. Describe the general structure of a QTL experiment, including the kind of tomato strains you would use, how molecular markers should be distributed in the genome, how the genetic marker alleles should differ between the two strains, and how you would use the F₁ progeny in a subsequent cross to obtain information about the possible location(s) of QTLs of interest.

Accepted Answer

Hi everyone. Let's take a look at this practice problem together. The variation in the phenotypic trait can be associated with the quantitative trait locus or Q T L A specific chromosome region may contain a Q T L. If that region frequently contains the answer options are a molecular markers. B mutations C coding sequences and D stop codon sequences. Now recall that a Q T L, what is that definition? It's the chromosomal location of a gene where that gene contributes to the phenotypic variation for a quantitative trait. So what specific chromosome region may contain A Q T L? Let's talk about option B. Now, while mutations can occur in the chromosome, their present is not always specific. And therefore, we can eliminate option B. Now codeine sequences and stop codon sequences are likely to be specific or have specific locations in the chromosome. However, they both pertain to translation and it does not, these sequences do not have specific relationships to Q T L S. So we can eliminate options C and D as well. The correct answer is molecular markers. Now recall an example of this is a single nucleotide polymorphism which is abbreviated SNP these are genetically linked to the Q T L and indicates that A Q T L is near or by the location of the SNP. And these molecular markers are used to map Q T L S. So again, the correct answer is option a molecular markers. All right, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.

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