12. Gene Regulation in Prokaryotes
Tryptophan Operon and Attenuation
2:48 minutes
Problem 15
Textbook Question
Textbook QuestionAttenuation of trp operon transcription is controlled by the formation of stem-loop structures in mRNA. The attenuation function can be disrupted by mutations that alter the sequence of repeat DNA regions 1 to 4 and prevent the formation of mRNA stem loops. Describe the likely effects on attenuation of each of the following mutations under the conditions specified.
Mutated Region Tryptophan Level
a. Region 1 Low
b. Region 1 High
c. Region 2 Low
d. Region 2 High
e. Region 3 Low
f. Region 3 High
g. Region 4 Low
h. Region 4 High
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