Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Probability and Genetics
4:39 minutes
Problem 44a
Textbook Question
Textbook QuestionSitus inversus is a congenital condition in which the major visceral organs are reversed from their normal positions. Investigations into the genetics of this abnormality revealed that individuals with at least one dominant allele (SI) of an autosomal gene are normal but, surprisingly, of individuals that are homozygous for a recessive allele (si), 1/2 are situs inversus and 1/2 are normal. What genotypes and phenotypes are expected in progeny from a cross of two SI si individuals?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Genotype and Phenotype
Genotype refers to the genetic constitution of an individual, specifically the alleles present at a given locus. Phenotype, on the other hand, is the observable physical or biochemical characteristics of an organism, which result from the interaction of its genotype with the environment. Understanding the distinction between these two concepts is crucial for predicting the traits of offspring in genetic crosses.
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Mendelian Inheritance
Mendelian inheritance describes the patterns of inheritance for traits controlled by single genes, as established by Gregor Mendel. It includes principles such as dominance, where dominant alleles mask the effects of recessive alleles, and segregation, which states that alleles segregate independently during gamete formation. These principles are essential for predicting the genotypes and phenotypes of progeny in genetic crosses.
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Punnett Square
A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross. It organizes the possible gametes from each parent and shows the potential combinations in the offspring. Utilizing a Punnett square for the cross of two SI si individuals will help visualize the expected ratios of genotypes and phenotypes in their progeny.
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